Preparation of a β-Cyclodextrin-Modified N-Carboxymethylchitosan and Its Chromatographic Behavior as a Chiral HPLC Stationary Phase

Efficient Separation of Enantiomers Using Stereoregular Chiral Polymers

“…In addition to cellulose and amylose, other polysaccharides, such as chitin, chitosan, xylan, dextran, etc., have also been used to prepare the CSPs for enantioseparation. ,,− Among these, the 3,5-dimethylphenylcarbamates of chitosan and xylan exhibited relatively higher recognition abilities for some racemates compared to those on the cellulose and amylose derivatives, implying the potential to develop new CSPs with a high chiral recognition ability. The chitosan possesses a structure similar to that of the cellulose except for the groups at the 2 position: the former has an amino group and the latter a hydroxy group. , The treatment of chitosan with a phenyl isocyanate affords a 3,6-diphenylcarbamates-2-urea derivative ( 82 in Figure ).…”

Structure Control of Polysaccharide Derivatives for Efficient Separation of Enantiomers by Chromatography

“…Besides the cellulose and amylose derivatives, various carbamate derivatives of polysaccharides, such as chitin, chitosan, galactosamin, xylan, dextran, curdlan, and inulin, have been prepared and applied as CSPs for HPLC. ,− Their recognition abilities significantly depend on the linkage positions, anomeric configurations, and nature of the monomeric units. Among them, the chitin ( 32 ) , and chitosan ( 33 ) derivatives as shown in Figure exhibited a relatively high recognition ability for a wide range of chiral compounds including drugs.…”

Synthesis, characterization, and metal ions adsorption properties of chitosan–calixarenes (I)

“…An α‐cyclodextrin (CD)‐linked CTS derivative has been prepared via a reductive amination strategy 7. A β‐CD‐modified N ‐carboxymethylchitosan has been synthesized as a chiral high‐performance liquid chromatography (HPLC) stationary phase 8…”