Structure Control of Polysaccharide Derivatives for Efficient Separation of Enantiomers by Chromatography

Chirality pairing recognition, a unique reaction forming spiral alkaloids from amino acids stereoselectively in one-pot

“…Although "molecular sex" was first used in nucleic acids hybridize studies 1 , and "molecular recognition" has been widely used in chiral compound separations, which via space match each other, however, they are physical behaviors. 2 In this report, we show the first chemical behavior example of chirality pairing recognition reaction or molecular sex recognition reactions where D-(+)-amino acid derivative could selectively react with the corresponding L-(-)-amino acid analog to form single product combined by D-and L-amino derivative (D-L) instead of mixtures of D-D and L-L products. Novel spiral alkaloid with unique sketch formed in the one-pot reactions.…”

Homochiral metal-organic framework [Zn2(d-Cam)2(4,4′-bpy)]nfor high-resolution gas chromatographic separations

“…6. The chiral recognition ability of [Zn 2 (D-Cam) 2 (4,4′-bpy)] n mainly comes from the surface of the crystals in which the steric fit is the main interactive force [48,49]. In addition, many other interactions, involving hydrogen bond, dipole-dipole, dispersion and van der Waals forces may also play some roles.…”

Cellulose Chemistry Meets Click Chemistry: Syntheses and Properties of Cellulose-Based Glycoclusters with High Structural Homogeneity

“…The reaction mixture was then diluted with ethyl acetate and washed with NaCl-saturated aqueous solution and deionized water repeatedly. The resultant organic layer was dried over anhydrous MgSO 4 …”

“…The resultant mixture was diluted with ethyl acetate and washed with NaHCO 3 saturated aqueous solution. The organic layer was dried over anhydrous MgSO 4 , filtered and concentrated to dryness. In the case of the maltoside, MALDI-TOF-MS and TLC analysis of the residue showed partially deacetylated product.…”

“…In addition, cellulose is advantageous as a chiral scaffold, since it has an enormous number of chiral centers. For example, silica gels coated with cellulose derivatives are now widely used as stationary phases for chiral separation [1][2][3][4]. Chemically modified celluloses find their application in pharmaceutical/medicinal areas because of their biocompatibility and biodegradability [5,6].…”