Preparation conditions and swelling equilibria of dextran hydrogels prepared by some crosslinking agents

Denizli, Betül Kırcı; Can, Hatıce Kaplan; Rzaev, Zakır M. O.; Güner, Ali̇

doi:10.1016/j.polymer.2004.07.067

Cited by 50 publications

(26 citation statements)

References 22 publications

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“…[22][23][24][25][26] Based on the Williamson etherification and the alkali-catalyzed oxalkylation, cellulose dissolved in NaOH/urea aqueous solution could be chemically crosslinked by ECH to form hydrogels, and without the addition of an extra base because of the basicity of the solvent system. Table 1 displays the reaction conditions and the yields of four cellulose hydrogels.…”

Section: Resultsmentioning

confidence: 99%

Hydrogels Prepared from Unsubstituted Cellulose in NaOH/Urea Aqueous Solution

Zhou

Chang

Zhang

et al. 2007

Macromolecular Bioscience

171

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Novel cellulose hydrogels were synthesized through a "one-step" method from cellulose, which was dissolved directly in NaOH/urea aqueous solution, by using epichlorohydrin as crosslinker. Structure and properties of the hydrogels were characterized by using SEM, NMR, and water absorption testing. The hydrogels are fully transparent and display macroporous inner structure. The equilibrium swelling ratios of the hydrogels in distilled water at 25 degrees C are in the range from 30 to 60 g H(2)O/g dry hydrogel. Moreover, the reswelling water uptake of the hydrogels could be achieved to more than 70% compared with their initial swelling states. This work provided a simple and fast method for preparing eco-friendly hydrogels from unsubstituted cellulose.

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Section: Resultsmentioning

confidence: 99%

Hydrogels Prepared from Unsubstituted Cellulose in NaOH/Urea Aqueous Solution

Zhou

Chang

Zhang

et al. 2007

Macromolecular Bioscience

171

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“…To obtain the network, chemical cross-linking (Denizli, Can, Rzaev, & Guner, 2004;Kiritoshi & Ishihara, 2004;Molina, Gomez-Anton, & Pierola, 2007;Zhao, Liao, Gao, & Liu, 2006), physical entanglement (Saito, Sakurai, Sakakibara, & Saga, 2003), ionic bonds (de la Torre, Torrado, & Torrado, 2003;Kang, Park, Lee, & Son, 2007;Masci, Husu, Murtas, Piozzi, & Crescenzi, 2003;Wong, Díez-Pascual, & Richtering, 2009) and hydrogen bonds (Jin, Liu, Zhang, Chen, & Niu, 2006) are used in the preparation of hydrogels. Polymer hydrogels have been widely utilized as drug delivery, food, cosmetics, high water-absorbing resin, contact lenses, corneal, implant, substitutes for skin, tendons, ligaments, cartilage, and bone, because of their excellent hydrophilicity, permeability, compatibility and low coefficient of friction (Calvert, 2009;Chang, Duan, Cai, & Zhang 2010;Chan, Whitney, & Neufeld, 2009;Liu & Fan, 2005;Yamamoto, Takahashi, & Tabata, 2003).…”

Section: Introductionmentioning

confidence: 99%

Structure and properties of hydrogels prepared from cellulose in NaOH/urea aqueous solutions

Chang

Zhang

Zhou

et al. 2010

Carbohydrate Polymers

250

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“…In this work, hydrogels based on pachyman and its derivatives can be easily prepared by ECH because ECH is a convenient, base-catalyzed crosslinking agent in polysaccharide chemistry [40][41][42]. Once the pachyman and CMP samples were completely dissolved in the alkaline solution, this bifunctional agent could easily crosslink with the hydroxyl group in the polysaccharide molecules.…”

Section: Results and Discussion Hydrogel Synthesismentioning

confidence: 99%

pH-sensitive interpenetrating network hydrogels based on pachyman and its carboxymethylated derivatives for oral drug delivery

Mei

2015

J Polym Res

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pH-sensitive, interpenetrating polymer network hydrogels were synthesized based on pachyman and its carboxymethylated derivatives (CMP) by the confunctional crosslinker agent epichlorohydrin. The structure and morphology of pachyman/CMP (CPCS) hydrogels were characterized. In the swelling assays, the composite hydrogels maintained remarkable swelling capacity and significant good pH sensitivity. The swelling behavior was much improved by the incorporation of CMP than the pure pachyman hydrogels. While increasing the content of CMP in the hydrogels, the equilibrium swelling time was more reduced and the swelling ratio increased obviously due to the better water solubility of CMP. In the drug release study, the results indicated that CPCS hydrogels demonstrate better pH-resistant sustained drug release for bovine serum albumin, and the adjustment of the proportion of pachyman to CMP results in improved drug release behavior, which suggests that the CPCS hydrogels are promising candidates for sustained drug delivery system.

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Preparation conditions and swelling equilibria of dextran hydrogels prepared by some crosslinking agents

Cited by 50 publications

References 22 publications

Hydrogels Prepared from Unsubstituted Cellulose in NaOH/Urea Aqueous Solution

Hydrogels Prepared from Unsubstituted Cellulose in NaOH/Urea Aqueous Solution

Structure and properties of hydrogels prepared from cellulose in NaOH/urea aqueous solutions

pH-sensitive interpenetrating network hydrogels based on pachyman and its carboxymethylated derivatives for oral drug delivery

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