Preparation, Antimicrobial Properties under Different Light Sources, Mechanisms and Applications of TiO2: A Review

Shang, Changyu; Bu, Junyu; Song, Cui

doi:10.3390/ma15175820

Cited by 12 publications

(9 citation statements)

References 151 publications

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“…Furthermore, when combined with photoactivation, hgel-TiO 2 NPs displayed augmented antibacterial activity, even at suboptimal concentrations like 0.05 mg/mL. This interplay between NP concentration and UV light exposure has been explored previously, reinforcing the role of UV light in enhancing NP-based antimicrobial strategies [48]. The present study also offers insightful revelations into how non-photoactivated TiO 2 NPs and hgel-TiO 2 NPs distinctly influence the metabolic activity of S. aureus.…”

Section: Antibacterial Studiessupporting

confidence: 68%

Biosynthesis of Peptide Hydrogel–Titania Nanoparticle Composites with Antibacterial Properties

Binaymotlagh,

Hajareh Haghighi,

Di Domenico

et al. 2023

Gels

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The photoantibacterial properties of titania nanoparticles (TiO2NPs) are attracting much interest, but the separation of their suspension limits their application. In this study, the encapsulation of commercial TiO2NPs within self-assembling tripeptide hydrogels to form hgel-TiO2NP composites with significant photoantibacterial properties is reported. The Fmoc-Phe3 hydrogelator was synthesized via an enzymatic method. The resulting composite was characterized with DLS, ζ-potential, SAXS, FESEM-EDS and rheological measurements. Two different concentrations of TiO2NPs were used. The results showed that, by increasing the TiO2NP quantity from 5 to 10 mg, the value of the elastic modulus doubled, while the swelling ratio decreased from 63.6 to 45.5%. The antimicrobial efficacy of hgel-TiO2NPs was tested against a laboratory Staphylococcus aureus (S. aureus) strain and two methicillin-resistant S. aureus (MRSA) clinical isolates. Results highlighted a concentration-dependent superior antibacterial activity of hgel-TiO2NPs over TiO2NPs in the dark and after UV photoactivation. Notably, UV light exposure substantially increased the biocidal action of hgel-TiO2NPs compared to TiO2NPs. Surprisingly, in the absence of UV light, both composites significantly increased S. aureus growth relative to control groups. These findings support the role of hgel-TiO2NPs as promising biocidal agents in clinical and sanitation contexts. However, they also signal concerns about TiO2NP exposure influencing S. aureus virulence.

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Section: Antibacterial Studiessupporting

confidence: 68%

Biosynthesis of Peptide Hydrogel–Titania Nanoparticle Composites with Antibacterial Properties

Binaymotlagh,

Hajareh Haghighi,

Di Domenico

et al. 2023

Gels

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“…Therefore, a high density of surface defects can cause a decreased intensity of the NBE emission [56]. The production of ROS was increased by the surface defects, especially by the oxygen vacancies, and therefore their density was correlated with a higher antimicrobial activity under light irradiation [57].…”

Section: Spectroscopic Studies 331 Uv-vis and Fluorescence (Pl) Spect...mentioning

confidence: 99%

Antibacterial Activity of Zinc Oxide Nanoparticles Loaded with Essential Oils

Motelica,

Vasile,

Ficai

et al. 2023

Pharmaceutics

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One major problem with the overuse of antibiotics is that the microorganisms acquire resistance; thus the dose must be increased unsustainably. To overcome this problem, researchers from around the world are actively investigating new types of antimicrobials. Zinc oxide (ZnO) nanoparticles (NPs) have been proven to exhibit strong antimicrobial effects; moreover, the Food and Drugs Administration (FDA) considers ZnO as GRAS (generally recognized as safe). Many essential oils have antimicrobial activity and their components do not generate resistance over time. One of the drawbacks is the high volatility of some components, which diminishes the antimicrobial action as they are eliminated. The combination of ZnO NPs and essential oils can synergistically produce a stronger antimicrobial effect, and some of the volatile compounds can be retained on the nanoparticles’ surface, ensuring a better-lasting antimicrobial effect. The samples were characterized with X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), ultraviolet-visible spectroscopy (UV-Vis), and thermal analysis (TG-DSC) coupled with analysis of evolved gases using FTIR. The ZnO NPs, with a size of ~35 nm, exhibited a loading between 1.44% and 15.62%—the lower values were specific for limonene-containing oils (e.g., orange, grapefruit, bergamot, or limette), while high values were obtained from cinnamon, minzol, thyme, citronella, and lavender oils—highlighting differences among non-polar terpenes and alcohol or aldehyde derivatives. The antibacterial assay indicated the existence of a synergic action among components and a high dependency on the percentage of loaded oil. Loaded nanoparticles offer immense potential for the development of materials with specific applications, such as wound dressings or food packaging. These nanoparticles can be utilized in scenarios where burst delivery is desired or when prolonged antibacterial activity is sought.

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“…Light-activated antimicrobial surfaces can excite electrons under a specific light, producing the reactive oxygen species (ROS) on the surface that degrade organic contaminants, including microbes. Titanium dioxide (TiO 2 ) is probably the best-known light-activated antimicrobial material and is widely used in antimicrobial coatings (Shang et al, 2022). For better stability and action under visible light, TiO 2 has been morphologically modified and doped with metal and non-metal elements (Nigussie et al, 2018;Schutte-Smith et al, 2023).…”

Section: Indoor Surfacesmentioning

confidence: 99%

Methods for infection prevention in the built environment—a mini-review

Salonen¹,

Ahonen²,

Sirén³

et al. 2023

Front. Built Environ.

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The COVID-19 pandemic has shown that infection prevention actions need to be more efficient in public indoor environments. In addition to SARS-CoV-2, the cause of COVID-19, many pathogens, including other infectious viruses, antibiotic-resistant bacteria, and premise plumbing pathogens, are an invisible threat, especially in public indoor spaces. The indoor hygiene concept for comprehensive infection prevention in built environments highlights that the indoor environment should be considered as a whole when aiming to create buildings with increased infection prevention capacity. Within indoor environments, infections can indirectly spread through surfaces, air, and water systems. Many methods, such as antimicrobial technologies and engineering solutions, targeting these indoor elements are available, which aim to increase the hygiene level in indoor environments. The architectural design itself lays a foundation for more efficient infection prevention in public buildings. Touchless solutions and antimicrobial coatings can be applied to frequently touched surfaces to prevent indirect contact infection. Special ventilation solutions and air purification systems should be considered to prevent airborne infection transmissions. Proper design and use of water supply systems combined with water treatment devices, if necessary, are important in controlling premise plumbing pathogens. This article gives a concise review of the functional and available hygiene-increasing methods—concentrating on indoor surfaces, indoor air, and water systems—to help the professionals, such as designers, engineers, and maintenance personnel, involved in the different stages of a building’s lifecycle, to increase the infection prevention capacity of public buildings.

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Preparation, Antimicrobial Properties under Different Light Sources, Mechanisms and Applications of TiO2: A Review

Cited by 12 publications

References 151 publications

Biosynthesis of Peptide Hydrogel–Titania Nanoparticle Composites with Antibacterial Properties

Biosynthesis of Peptide Hydrogel–Titania Nanoparticle Composites with Antibacterial Properties

Antibacterial Activity of Zinc Oxide Nanoparticles Loaded with Essential Oils

Methods for infection prevention in the built environment—a mini-review

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