Preparation and Properties of PHEA/Chitosan Composite Hydrogel

Kim, Jeong Hoon; Sim, Sang Jun; Lee, Dong Hoon; Kim, Dong Jin; Lee, Youngkwan; Chung, Dong June; Kim, Ji Heung

doi:10.1295/polymj.36.943

Cited by 27 publications

(18 citation statements)

References 16 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The cytotoxicity test of samples were done according to ISO 10993-5. The L929 cells [32] are commonly used model cell type for studying cytotoxic effect of samples. L929 cells were cultured in minimum essential medium (MEM) supplemented with 10% fetal bovine serum (FBS), 50 IU ml −1 penicillin, 50 g ml −1 streptomycin (Invitrogen, CA, USA) at 37 • C in a humidified 5% CO 2 atmosphere.…”

Section: Cytotoxicity Testmentioning

confidence: 99%

Chitosan-PVP-nano silver oxide wound dressing: In vitro and in vivo evaluation

Archana

Singh

Dutta

et al. 2015

International Journal of Biological Macromolecules

300

127

View full text Add to dashboard Cite

Section: Cytotoxicity Testmentioning

confidence: 99%

Chitosan-PVP-nano silver oxide wound dressing: In vitro and in vivo evaluation

Archana

Singh

Dutta

et al. 2015

International Journal of Biological Macromolecules

300

127

View full text Add to dashboard Cite

“…To overcome this shortcoming, biodegradable hydrogels were then proposed in more recent years 3, 15. But the reports on potentially applicable hydrogels as drug delivery system with both intelligence and biodegradability as well as other necessary characteristics are still rather limited 21–25. In this work, we prepared a new kind of biodegradable and pH‐responsive P(CL‐MAA‐EG) hydrogel from polycaprolactone, methacrylic acid, and poly(ethylene glycol).…”

Section: Introductionmentioning

confidence: 99%

Synthesis, characterization, and hydrolytic degradation behavior of a novel biodegradable pH‐sensitive hydrogel based on polycaprolactone, methacrylic acid, and poly(ethylene glycol)

Guo

Qian

Huang

et al. 2007

J Biomedical Materials Res

View full text Add to dashboard Cite

In this work, a new kind of biodegradable pH-sensitive hydrogel was successfully synthesized by UV-initiated free radical polymerization. The obtained hydrogel was characterized by (1)H NMR and FTIR. Swelling behavior in different aqueous media and pH responsivity of the hydrogels were studied in detail as well. With increase in pH from 1.2 to 7.2, swelling ratio of the hydrogel increased. The morphology was observed by scanning electron microscopy, and the hydrolytic degradation behavior was also investigated in this work.

show abstract

“…Poly (urethane) hydrogels serve as drug matrices, artificial kidney membranes, and catheter coating materials [187].…”

Section: Hydrogels For Pharmaceutical Applicationsmentioning

confidence: 99%

A Review on Recent Advances in Stabilizing Peptides/Proteins upon Fabrication in Hydrogels from Biodegradable Polymers

Raza

Zafar

Zhu

et al. 2017

Preprint

View full text Add to dashboard Cite

Hydrogels evolved as an outstanding carrier material for local and controlled drug delivery that tend to the shortcomings of old conventional dosage forms for small drugs (NSAIDS) and large peptides and proteins. Aqueous swellable and crosslinked polymeric network structure of hydrogels is composed of various natural, synthetic and semisynthetic biodegradable polymers. Hydrogels have remarkable properties of functionality, reversibility, sterilizability, and biocompatibility. All these dynamic properties of hydrogels have increased the interest in their use as a carrier for peptides and proteins to be released slowly in a sustained manner. The therapeutical peptide and proteins are remarkable therapeutic agents in today's world that allows the treatment of severe, chronic and life-threatening diseases, such as diabetes, rheumatoid arthritis, hepatitis in an easy manner. Despite few limitations, hydrogels provide fine tuning of proteins and peptides delivery with enormous impact in clinical medicine. The primary objective of this article is to review current issues concerned with the therapeutics peptides and proteins and impact of remarkable properties of hydrogels on these therapeutic agents. Different routes for pharmaceutical peptides and proteins and superiority over other drugs candidates are presented. The article will also review literature concerning classification of hydrogels on different basis, polymers used, release mechanisms their physical and chemical characteristics and diverse applications.

show abstract

Preparation and Properties of PHEA/Chitosan Composite Hydrogel

Cited by 27 publications

References 16 publications

Chitosan-PVP-nano silver oxide wound dressing: In vitro and in vivo evaluation

Chitosan-PVP-nano silver oxide wound dressing: In vitro and in vivo evaluation

Synthesis, characterization, and hydrolytic degradation behavior of a novel biodegradable pH‐sensitive hydrogel based on polycaprolactone, methacrylic acid, and poly(ethylene glycol)

A Review on Recent Advances in Stabilizing Peptides/Proteins upon Fabrication in Hydrogels from Biodegradable Polymers

Contact Info

Product

Resources

About