Preparation and properties of pH-responsive, self-assembled colloidal nanoparticles from guanidine-containing polypeptide and chitosan for antibiotic delivery

pH-responsive casein-based films and their application as functional coatings in solid dosage formulations

“…In the last few years, strict health regulations and consumer preferences have driven the use of natural polymers due to their recognized/known non-toxicity as vehicles [13]. In this context, polypeptides and proteins are a promising alternative as building blocks of novel drug delivery systems, due to their excellent functional properties, high biocompatibility and easy degradation by enzymatic action under physiological conditions [14][15][16]. Among the different commercially available proteins, casein has gained notoriety due to its structural and physicochemical properties that facilitate its use in drug delivery systems [17].…”

Sulfaguanidine nanofiltration active layer towards anti-adhesive and antimicrobial attributes for desalination and dye removal

“…Polymers containing guanidine or biguanidine groups have attracted substantial interest and proved to be effective cationic antimicrobial and biocidal agents. 25,26 The guanidine-based polymers have shown outperforming properties over other antimicrobials, such as the exceptional broad-spectrum antimicrobial activity, excellent biocide efficiency and low toxicity to mammalian, thus enjoy increasing applications in industry, therapy and the clinic. 27,28 The antibacterial activity of polymeric guanidine is ascribed to the progressive interaction between the cationic guanidine and the negatively charged groups including phospholipids, proteins and lipopolysaccharides on the bacterial cell membrane surface.…”

A Novel Biodegradable Hollow Nanocarrier Consisting Superparamagnetic Fe₃O₄-loaded poly-γ- glutamic Acid and Chitosan Oligosaccharide for Targeted Delivery of Sulforaphane from Broccoli Seed Extracts

“…Based on the positively charged surface of CO and the negatively charged one of γ-PGA, CO/γ-PGA polyelectrolyte complexes is benefited to us to form various kinds of nanomaterials in simple method 1) . Many CO and γ-PGA composites, such as nanoparticles [2][3][4][5][6] , hydrogels 7) , and microcapsules 8) , have been reported as drug carriers. CO are biocompatible and biodegradable, and demonstrate antibacterial effects.…”