Preparation and evaluation of some benzimidazole derivatives as antioxidants for local base oil

Basta, J. S.; El-Bassoussi, A. A.; Salem, A.; Nessim, M.I.; Ahmed, Mohammed H.; Attia, Sayed K.

doi:10.1016/j.ejpe.2016.10.001

Cited by 15 publications

(5 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Consequently, the addition of antioxidants became very required to protect the oil by decreasing the oxidative degradation during industrial application [5]. Most of the heterocyclic compounds which have compact structure possess antioxidant, anticorrosion and antiwear properties [6][7][8]. Heterocyclic compounds have been reported as antiwear and extreme pressure additives such as thiadiazoles and benzotriazoles [9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Studies On Some Thiazolidinones As Antioxidants For Local Base Oil

et al. 2019

View full text Add to dashboard Cite

I N THIS work, 5 thiazolidinone derivatives of the type 5-benzylidene -2-(1-piperidinyl)- (105) are synthesized and characterized using conventional tools analyses. They are tested as antioxidants for local base stock and the efficiency of these compounds, as antioxidants, was monitored through studying the change in total acid number and viscosity, the results reveal that the efficiency order is ranked as follows 105 < 104 < 103 <102 < 101. The quantum chemical parameters such as the lowest unoccupied molecular orbital (LUMO), the highest occupied molecular orbital (HOMO) energy levels and the energy gap (E HOMO -E LUMO ) were calculated. The experimental results were on the same line with the quantum chemical calculations.

show abstract

Section: Introductionmentioning

confidence: 99%

Studies On Some Thiazolidinones As Antioxidants For Local Base Oil

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Se ha documentado que los benzimidazoles cumplen una función antioxidante en bases oleicas de origen vegetal e hidrocarburos (Basta et al, 2016;Komatsu, Souza, Carvalho, de Campos, & Totten, 2010), por lo cual es importante que se lleve a cabo una valoración posterior de este efecto del tiabendazol en los aceites utilizados.…”

Section: -124unclassified

Efecto de agroinsumos y aceites esenciales sobre el suelo de hortalizas en el Caribe Colombiano

Mena-Rodríguez

Ortega-Cuadros

Merini

et al. 2017

CTA

View full text Add to dashboard Cite

El aporte de las hortalizas a la seguridad alimentaria y desarrollo económico de Colombia y la problemática ambiental mundial, justifica el interés de diseñar estrategias productivas sostenibles para la agrocadena. Se desarrolló un estudio para evaluar el efecto de la aplicación de aceites esenciales y agroinsumos en cultivos de ají, fríjol y berenjena en Codazzi, Cesar. La metodología comprendió el análisis de compatibilidad entre pesticidas utilizados en estas hortalizas, aceites de Lippia alba y Cymbopogon citratus, respecto al efecto biocida in vitro sobre cepas nativas de Macrophomina phaseolina, Phytophthora capsici y Colletotrichum gloeosporioides. En campo, se aplicó tiabendazol individual y combinado con los aceites. Se midieron indicadores fisicoquímicos y microbiológicos de suelo, incidencia de plagas y enfermedades y rendimiento de cultivos. Los aceites controlaron in vitro hasta el 97 % de fitopatógenos y exhibieron compatibilidad con carbendazim y tiabendazol. En campo, se observó control de enfermedades hasta del 67 % con C. citratus + tiabendazol respecto al testigo (P=0,00), rendimientos cercanos al promedio regional, mejores condiciones microbiológicas y fisicoquímicas del suelo. En conclusión, existen diferencias en el efecto edáfico entre tratamientos, fue más favorable la combinación de aceites y el agroquímico respecto al efecto individual de cada producto sobre las variables evaluadas. Lo anterior exhorta a continuar evaluaciones en campo con aceites para elucidar la duración de los efectos descritos.

show abstract

“…[ 14 ] In recent years, antioxidant activity of compounds containing a benzimidazole ring has been considered. [ 15–19 ]…”

Section: Introductionmentioning

confidence: 99%

Antioxidant and DNA damage protecting activities of newly synthesized thiol bridged bis‐benzimidazole derivative and its dicationic analogue

Yıldız

2020

Journal of Heterocyclic Chem

View full text Add to dashboard Cite

Two new types of bis‐benzimidazole derivatives containing thiol group have been prepared and characterized. The compounds contain sulfur with imidazole ring show promising biological activities such as antioxidant, anticancer, antimicrobial and etc. The aim of this study was synthesis of benzimidazole derivatives which not only show antioxidant activity but also protect DNA from oxidative damage. Antioxidant activities of the synthesized compounds were investigated with DPPH and hydrogen peroxide radical scavenging assays. DNA nicking assay was applied to establish activity of compounds to protect plasmid DNA from Fenton's reagent radicals. Both compounds had antioxidant activity, however, activity of dicationic analogue was greater than well‐known antioxidant Vit C. IC50 values calculated according to DPPH method were 14.5 μM for dicationic analogue (2) and 57.5 μM for 1,2‐bis(1‐methyl‐1H‐benzo[d]imidazol‐2‐ylthio)ethane (1). In hydrogen peroxide scavenge assay IC50 values of compounds were 638.6 μg/mL for 1,2‐bis(1‐methyl‐1H‐benzo[d]imidazol‐2‐ylthio)ethane (1), 398.9 μg/mL for dicationic analogue (2). Furthermore, dicationic analogue promised an effective DNA protection due to its positive charge interacting with negatively charged DNA. Also the high solubility of the dicationic analogue in water due to its positive charge could provide a great advantage in biological applications.

show abstract

Preparation and evaluation of some benzimidazole derivatives as antioxidants for local base oil

Cited by 15 publications

References 10 publications

Studies On Some Thiazolidinones As Antioxidants For Local Base Oil

Studies On Some Thiazolidinones As Antioxidants For Local Base Oil

Efecto de agroinsumos y aceites esenciales sobre el suelo de hortalizas en el Caribe Colombiano

Antioxidant and DNA damage protecting activities of newly synthesized thiol bridged bis‐benzimidazole derivative and its dicationic analogue

Contact Info

Product

Resources

About