Preliminary Phytochemical and GC-MS analysis of chemical constituents of Iraqi Plantago lanceoleta L.

Khalaf, Hasan Alaa Aldeen; Mahdi, Monther F.; Abaas, Ibrahim S.

doi:10.32947/ajps.v18i2.485

Cited by 4 publications

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“…In this plant extract is found to be more potent versus (+ve) bacteria. [17][18][19]. Due to its effectiveness versus the majority of (+ve, -ve ) bacteria tested, the extract has a wide spectrum of activity [20][21].…”

Section: Resultsmentioning

confidence: 99%

Antibacterial Activity and Extraction of Triterpenoid to lantana camara L. in Iraq

Hamed,

Falih,

Abed

2023

IOP Conf. Ser.: Earth Environ. Sci.

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Lantana camara belongs to the family Verbenaceae. This family consists of more than 100 genera and contains nearly 2600 species. Many of these species are of tropical or subtropical region. L. camara is cultivated as decorative plant or for making a boundary in a garden or field. Whole Lantana camara extracts are used to treat asthma, measles, and various types of cancer. The study aims to extract the triterpenoid within the plant lantana considering the environment in Iraq. Various separation methods based on temperature graduate were employed. Several solvents, including ethanol and hexane, were employed. The activity of triterpenoid as an antibacterial agent against a number of pathogenic species (Streptococcus pyogenes, Staphylococcus aureus, Escherichia coli, Klebsilla aeroganas). The disc diffusion method was used and the inhibition zones of different concentration were calculated. A triterpenoid extract was found very active against all type bacteria. Against Gram-positive Streptococcus pyogens, triterpenoid extract showed significant inhibition and weak inhibition against Gram-negative Escherichia coli.

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Section: Resultsmentioning

confidence: 99%

Antibacterial Activity and Extraction of Triterpenoid to lantana camara L. in Iraq

Hamed,

Falih,

Abed

2023

IOP Conf. Ser.: Earth Environ. Sci.

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“…The full-scan mass spectra were recorded at 10,000 u/s over the mass range (m/z) 25-1000. Peaks and chemical components were identified based on retention time by direct searching in the NIST (National Institute of Standards and Technology library) [13].…”

Section: Gc-ms Analysis Conditionsmentioning

confidence: 99%

Chemotaxonomy Significant in Delimitation of Six Taxa of Euphorbia L. in Iraq

Jassim,

Al-Newani

2023

IOP Conf. Ser.: Earth Environ. Sci.

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Six taxa of Euphorbia L. (E. hirta L., E. milii var. milii, E. milii cv. White, E. prostrata Aiton, E. hypericifolia L. and E. serpens Kunth) collected from different location in Baghdad were extracted and the phytochemical screening of hexane crude extracts of six taxa of Euphorbia revealed that the most distributed phytochemical compounds were saponins in all taxa except E. prostrata, however, alkaloids have been reported in E. hypericifolia, E. milii cv. White and E. milii var. milii, on the other hand, glycosides have been stated in E. prostrata and E. serpens. Flavonoids and phenols have been noticed in E. serpens only, while terpenes and tannins found in E. prostata and E. hirta respectively. However, the Gas Chromatography-Mass Spectrum of methanol extract of six taxa of Euphorbia analysis explained the presence of twenty seven different chemical compounds and two new terpenoids (trans-Geranylgeraniol and Squalene) from E. milii cv. White. Agglomerative Hierarchical cluster analysis (AHC) stated close chemical relations between all the studied species, the first group comprises E. hirta and E. hypericifolia showed close relationship due to the presence of natural compounds as fatty acids, esters and aromatic alcohols However, E. prostata and E. serpens were close correlated in one group together which characterized by presence of phenols, esters and fatty acids. The anthor group contains E. milli var. milli and E. milli cv. White characterized by the abundance of di- and tri-terpenoids in addition to other natural chemical products.

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Antiproliferative activity of Brassica nigra seeds extract in liver tissue of mice exposed to phenobarbital

Salman

Hanna

Mshimesh

2022

AJPS

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Hepatocellular proliferation is one of the most common causes of hepatocellular carcinoma (HCC), a type of cancer that is widely distributed disease. Hepatocellular carcinoma treatment has numerous barriers, including ineffectiveness, side effects, and drug resistance to currently available treatments. Previous studies showed that a high intake of Brassica vegetables has been associated to a decreased risk of a number of malignancies. The aim of this study is the evaluation of antiproliferative activity of Brassica nigra seeds extract in mice exposed to phenobarbital. Brassica nigra seeds where extracted; phytochemical analysis of the extract was done that including phytochemical screening tests and Gas chromatography-mass spectrometry (GC-MS) analysis. Antiproliferative activity of hydro alcoholic Brassica seeds extract has been studied by 800mg/kg and compare with control group (given normal saline), phenobarbital group (Phenobarbital 75mg/kg) and combination group (Brassica extract 800mg/kg+ Phenobarbital 75mg/kg). The GC-MS analysis revealed the presence of isothiocynate compound. Histologically phenobarbital induced severe hepatocellular proliferation (hyperplasia and hypertrophy), glass ground cytoplasm, while Brassica seeds extract produce improvement in histopathological changes that include mild scattered proliferation picture and eosinophilic cytoplasm. In comparison to phenobarbital group, Combination groups pretreated with Brassica nigra seeds for 14 days and phenobarbital for 7 days caused significant reduction relative liver weight and alanine aminotransferase (ALT) Brassica nigra seeds extract have isothiocynate as main compound it showed antiproliferative action on the liver tissue, implying that it may have a promising effect in minimizing the risk of liver cancer.

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Preliminary Phytochemical and GC-MS analysis of chemical constituents of Iraqi Plantago lanceoleta L.

Cited by 4 publications

References 0 publications

Antibacterial Activity and Extraction of Triterpenoid to lantana camara L. in Iraq

Antibacterial Activity and Extraction of Triterpenoid to lantana camara L. in Iraq

Chemotaxonomy Significant in Delimitation of Six Taxa of Euphorbia L. in Iraq

Antiproliferative activity of Brassica nigra seeds extract in liver tissue of mice exposed to phenobarbital

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