Pregnancy Outcome in Gestational Diabetes Mellitus

Bajracharya, Amir; Saha, Rachana; Shakya, Archana

doi:10.3126/jkmc.v3i3.12246

Cited by 4 publications

(4 citation statements)

References 17 publications

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“…42% of newborn needed admission in NICU for various reason which is higher than 28.7% reported in one study done by Ostlund I et al22 . This study revealed that 4(8%) neonates developed RDS (Respiratory distress syndrome) and 5(10%) newborns had hypoglycemia which is in concordance with one study done by Bajracharya et al where the incidence is 4.4% and 8.89% respectively23 . There is no congenital anomale or neonatal death in this study due to universal screening and early diagnosis and strict blood sugar control during antenatal period.…”

supporting

confidence: 91%

Study of Risk Factors and Foeto-maternal Outcome of Gestational Diabetes Mellitus

Chisty,

Alam

2023

J. Armed Forces Med. Coll.

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Introduction: Gestational diabetes mellitus (GDM) is a common pregnancy complication with complex disease mechanism. Several risk factors may contribute to its onset. Based on recent evidence up-to 15% of all pregnancies may be affected by GDM. Untreated GDM is a severe threat to maternal and neonatal health Objectives: To determine the risk factors and foeto- maternal outcome of GDM. Methods: This prospective observational study was conducted on patients who were admitted in Obstetrics & Gynaecology department of CMH, Bogura from June 2020 to May 2021 with the diagnosis of GDM. Data were collected from the patients as well as from the antenatal records in a preformed questionnaire and risk factors and outcomes measured. Results: A total of 679 patients were admitted during the period of 1 year from June 2020 to May 2021. Among them 50 patients were admitted with GDM. The prevalence of GDM was 7.36%. GDM risks were higher in women aged between 25-29 years and in those with maternal overweight and obesity (58%). Newborns of GDM mother had an increased risk of hypoglycemia (10%), macrosomia (20%), respiratory distress syndrome (8 %) and 42% required NICU admission. Most of the patients (92%) needed cesarean section. Conclusion: Pre-pregnancy BMI and family history of diabetes in first degree relatives and high parity were the predominant risk factor of GDM in this study. GDM patients are of increase risk of delivery by cesarean section, preterm birth, Newborns of GDM mother are at risk of RDS (Respiratory distress syndrome), macrosomia and neonatal hypoglycemia. JAFMC Bangladesh. Vol 18, No 2 (December) 2022: 46-50

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supporting

confidence: 91%

Study of Risk Factors and Foeto-maternal Outcome of Gestational Diabetes Mellitus

Chisty,

Alam

2023

J. Armed Forces Med. Coll.

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“…Prevalence of GDM in a study done in Tribhuvan University Teaching Hospital (TUTH) Kathmandu was 0.6%, in Dhulikhel Hospital, it was 0.75% and in Kathmandu Medical College, it was 1.58%. [24][25][26] In all these studies screening test was done with 50 gm GCT and confirmation done with 75 gm OGTT. These studies were done long time back as compared to our study.…”

Section: Discussionmentioning

confidence: 99%

“…11 GDM is in increasing trend world wide, 7,12,14,15 and same can be seen in Nepal. [24][25][26][27][28][29] Maternal age is strongly associated with GDM. In many studies it was reported that prevalence of GDM is increased with maternal age.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Gestational Diabetes, Risk Factors and its Outcome in a Tertiary Hospital

Shreshta¹,

Shrestha²

2018

Nep. Med. Coll. J.

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Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. GDM increases the risk of adverse maternal and perinatal outcome and increases risk of diabetes in mother and child in the future. Prevalence of GDM is increasing all over the world. This is hospital based cross sectional study done in Department of Obstetrics and Gynecology, Nepal Medical College and Teaching Hospital to find out the prevalence of GDM and to trace maternal and fetal risk factors and adverse outcome. In this study, 600 pregnant women were enrolled during 2016-17. Among them 27 (4.5%) were found to have GDM. Among GDM, four (14.4%) were ≥ 35 years old and six (22.2%) had BMI of ≥ 25 kg/m2. Caesarean section was more common mode of delivery in women with GDM than without (51.9% vs 22.2%). Increased prevalence shown in this study necessitates universal screening of GDM.

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“…2 The incidence of gestational diabetes mellitus was 1.58% in Kathmandu Medical College Teaching Hospital in the year 2014. 3 The GDM cases are at risk of developing a number of serious obstetric as well as long-term metabolic morbidity to women and their newborns. 4,5 Usually, screening for GDM is done at 24 to 28 weeks of pregnancy.…”

Section: Introductionmentioning

confidence: 99%

Level of glycosylated haemoglobin in the first trimester in cases of gestational diabetes mellitus

Gautam

Saha²,

Maharjan

et al. 2021

J. Kathmandu Med. Coll.

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Background: Glycosylated haemoglobin (HbA1c) level during early pregnancy has been proposed as a predictor of gestational diabetes mellitus (GDM). Objectives: To determine the mean value of first trimester’s glycosylated haemoglobin (HbA1c) in gestational diabetes mellitus cases. Methods: An analytical cross-sectional study was conducted among GDM cases at the Obstetrics and Gynaecology Department of Kathmandu Medical College after ethical clearance. Purposive sampling was done to enrol 102 cases that presented over a period of August 2020 to January 2021. First trimester HbA1c levels were recorded. The HbA1c values were grouped into two taking 5.7% as a cut-off which is an established threshold for prediabetes in a normal population. Results: The mean age of participants was 28.74 ± 4.1 years and mean body mass index was 29.13 ± 2.73 kg/m2. Mean value of HbA1c was 5.52 ± 0.44%. Mean value of fasting blood glucose and postprandial glucose after oral glucose tolerance test (OGTT) was 102.25 ± 7.36 mg/dl and 167.55 ± 10.91 mg/dl respectively. Out of total participants, only 40 (39.21%) had HbA1c value more than 5.7% while 62 (60.78%) had HbA1c value less than 5.7%. There was weak positive correlation between HbA1c and Fasting Blood Glucose (Pearson’s correlation coefficient r = 0.13). Similarly, correlation between HbA1c and blood sugar after OGTT (r = 0.17) was also insignificant. Conclusion: This study concluded that the HbA1c value of first trimester is not very different than normal population. Hence, diabetic range of HbA1c value in first trimester is useful in diagnosing overt diabetes.

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Pregnancy Outcome in Gestational Diabetes Mellitus

Cited by 4 publications

References 17 publications

Study of Risk Factors and Foeto-maternal Outcome of Gestational Diabetes Mellitus

Study of Risk Factors and Foeto-maternal Outcome of Gestational Diabetes Mellitus

Prevalence of Gestational Diabetes, Risk Factors and its Outcome in a Tertiary Hospital

Level of glycosylated haemoglobin in the first trimester in cases of gestational diabetes mellitus

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