Objective: Test the antioxidant activity of banana peel extract, watermelon rind extract, and combinations, also in lotion dosage form.
Methods:The antioxidant activity of each extract and their combinations were tested with 2,2-diphenyl-1-picrylhydrazil method and formulated into a lotion dosage forms. Evaluation of the lotion dosage forms, including organoleptic, homogeneity, pH, viscosity and rheology, microbiology, acute dermal irritation test, as well as the antioxidant activity test.Results: Antioxidant activity test on the extract showed inhibitory concentration 50% (IC 50
Conclusion:Lotion dosage form formula that meets the requirements of quality, efficacy, and safety with the best antioxidant activity is lotion dosage form combination of banana peel and watermelon rind extract formula (IC 75 :IC 25 ).