Predictors of and Satisfaction with Bilateral Prophylactic Mastectomy

Stefanek, Michael; Helzlsouer, Kathy J.; Wilcox, Patti M.; Houn, Florence

doi:10.1006/pmed.1995.1066

Cited by 153 publications

(85 citation statements)

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“…Indicators for choosing a (contralateral) prophylactic mastectomy ((C)PM) are being a carrier of a BRCA1/2 mutation [4,19,51], physician's advice [51], elevated cancer anxiety [38,55], parenthood [36], and number of affected relatives [4,49].…”

Section: Psychological Variablesmentioning

confidence: 99%

“…Several studies showed that elevated cancer worry or cancer anxiety had a positive influence on opting for surgery [38,55]. Stefanek et al [55] indicated that breast cancer related worry may influence the selection for PM in women (N = 164) with an elevated risk (at least one FDR with breast cancer).…”

Section: Psychological Variablesmentioning

confidence: 99%

“…Stefanek et al [55] indicated that breast cancer related worry may influence the selection for PM in women (N = 164) with an elevated risk (at least one FDR with breast cancer). Women who did not express interest in surgery reported fewer biopsies and a lower subjective breast cancer risk.…”

Section: Psychological Variablesmentioning

confidence: 99%

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Predictors of choosing life-long screening or prophylactic surgery in women at high and moderate risk for breast and ovarian cancer

2008

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The aim of this study is to summarize published empirical data describing the predictors of adhering to screening practices and choosing to have prophylactic surgery in women at increased risk for breast and ovarian cancer. Pubmed, Psychinfo and Cinahl databases were searched to identify studies on the predictors of adherence to breast and ovarian cancer screening and predictors of having a prophylactic mastectomy or salpingo-oophorectomy. We found 37 empirical studies that met our inclusion criteria. The main predictors of the use of preventive measures are related to DNA test results, socio-demographic characteristics, and psychological outcome measures. It is concluded that there is no unequivocal relationship between age, education, risk perception, or anxiety and adherence to breast and ovarian cancer screening practices. Worrying about cancer is associated with a higher adherence to screening practices.

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Section: Psychological Variablesmentioning

confidence: 99%

Section: Psychological Variablesmentioning

confidence: 99%

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Predictors of choosing life-long screening or prophylactic surgery in women at high and moderate risk for breast and ovarian cancer

2008

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“…Prophylactic mastectomy, whether or not followed by reconstructive surgery, must be discussed case by case with the patient, who should be well informed about the risks related to the surgical operation, the psychological changes it may bring and the incomplete protection it provides. Nevertheless, several studies showed that proven BRCA mutation carriers did not express any regret if the prophylactic mastectomy followed adequate counselling nor did they report sexual function changes after surgery; conversely their fear of cancer was effectively relieved (Stefanek et al 1995, Klijn et al 1997, Borgen et al 1998. Moreover, in another two studies, 35 and 17% of proven carriers of BRCA1 mutation declared an interest in prophylactic mastectomy, and 73 and 33% in prophylactic oophorectomy, shortly after disclosure of DNA-test results (results from Lerman et al 1996 andLynch et al 1997 respectively).…”

Section: Prophylactic Surgerymentioning

confidence: 99%

Management of risk of breast carcinoma in postmenopausal women.

Biglia¹,

Defabiani

Ponzone

et al. 2004

Endocr Relat Cancer

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Breast carcinoma is the most frequent tumor in the female population. Many factors can influence the risk of breast cancer; some of them, such as old age and breast cancer 1/2 (BRCA1/BRCA2) gene mutations, are associated with a fourfold increase in risk. A previous diagnosis of atypical ductal or lobular hyperplasia or having a first-degree relative with a carcinoma are factors associated with a twoto fourfold increase in risk. A relative risk between 1 and 2 is associated with longer exposure to endogenous hormones as a result of early menarche, late menopause and obesity, or with recent and prolonged use of hormone replacement therapy (HRT) or with behavioural factors such as high alcohol and fat intake.Is it possible to modify breast cancer risk in postmenopausal women? Risk factors related to lifestyle can be changed, even if it is not clear whether modifying these behavioural factors during the postmenopausal period will influence the overall breast cancer risk. For instance, the influence of exogenous hormones throughout life (both oral contraceptives and HRT) should be evaluated according to the individual risk-benefit ratio.The problem is even more complex for women who carry genetic mutations and for those who have close relatives with breast cancer, who may be candidates for risk reduction strategies. Prophylactic bilateral mastectomy is still controversial, but is frequently offered to or requested by this group of women and may be indicated in BRCA1/BRCA2 carriers. Chemoprevention with tamoxifen and with the new selective estrogen receptor modulators, namely raloxifene, is very promising and deserves a thorough discussion for all high-risk women.

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“…One study has shown that women at high risk of breast cancer who are undergoing prophylactic surgery were satisfied with their decision, although comfort with reconstruction was mixed (Stefanek et al, 1995). Another study reported that 5% had later regrets about the surgery (Borgen et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

Satisfaction and prosthesis related complaints in women with immediate breast reconstruction following prophylactic and oncological mastectomy

Contant

Wersch

Menke-Pluymers

et al. 2004

Psychology, Health & Medicine

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Aim: This study evaluated patient"s satisfaction with immediate breast reconstruction (IBR) with silicone prosthesis. Special attention is paid to the differences in satisfaction, and specific prosthesis related complaints of IBR after prophylactic and oncological mastectomy. Results:The most important perceived advantage of IBR was not to have to wear an external prosthesis (95%). Despite the fact that one third of the patients had specific prosthesis related complaints, 80% was satisfied with IBR and 88% would do it again. There was no significant difference in satisfaction between the prophylactic and the cancer group. Overall satisfaction is mostly influenced by cosmetics (r =-.58), information (r =-.45) and specific prosthesis related complaints (r =-.39). Especially specific prosthesis related complaints are important for both the prophylactic and the cancer group. Conclusions:The majority of patients were satisfied with IBR after oncological or prophylactic mastectomy. However the findings of the importance of specific prosthesis related complaints should be taken serious for the information and care of patients.Keywords: immediate breast reconstruction, silicone prosthesis, oncological and prophylactic mastectomy 3

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Predictors of and Satisfaction with Bilateral Prophylactic Mastectomy

Cited by 153 publications

References 0 publications

Predictors of choosing life-long screening or prophylactic surgery in women at high and moderate risk for breast and ovarian cancer

Predictors of choosing life-long screening or prophylactic surgery in women at high and moderate risk for breast and ovarian cancer

Management of risk of breast carcinoma in postmenopausal women.

Satisfaction and prosthesis related complaints in women with immediate breast reconstruction following prophylactic and oncological mastectomy

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