Predictive value of serum bilirubin level for identifying term neonates at risk for subsequent hyperbilirubinemia

Sriram, Gangina; Paramahamsa, R Rama Krishna

doi:10.18203/2349-3291.ijcp20193626

Cited by 3 publications

(3 citation statements)

References 12 publications

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“…~ 40 ~ Kadambi et al [11] in their study correlated thyroid Profile and serum bilirubin levels assessed in term neonates at 72 hours of life on 105 term neonates born through cesareansection. [12] found that newborns who developed significant hyperbilirubinemia male: female ratio was 1.07:1. 9 (33%) newborns with significant hyperbilirubinemia had jaundice in previous siblings.…”

Section: Discussionmentioning

confidence: 97%

Association between thyroid profile and serum bilirubin levels in term neonates on day 3 of life

Hitender¹,

Kiran²,

Himanshu³

2020

Int. J. Paediatrics Geriatrics

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Background: The present study was conducted to correlate thyroid profile and serum bilirubin levels assessed in term neonates on day 3 of life. Materials & Methods: The present study was conducted on146 neonate's ≥37 weeks of gestational age of both genders. Birth weight, gestational age, thyroid profile (T3, T4, TSH), serum bilirubin level (SBR) was calculated. Results: The mean gestational age was 272.4 days, birth weight was 2.8 Kgs, total bilirubin was 11.35 mg/dl, direct bilirubin was 0.46 mg/dl, fT3 level was 8.24 pg/ml, fT4 was 2.18 ng/dl and TSH was 4.08 mlU/ml. Normal expected neonates had normal T3, T4, TSH, TSB and direct Bilirubin level whereas 4 neonates had T3 level that ranged from 94-109, T4 from 5.8-8.2, TSH from 11.2-13.94, TSB from 10.2-16.2 and direct bilirubin from 0.31-0.54. Conclusion:Authors found no significant association between serum TSH and SBRT in term neonates.

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Section: Discussionmentioning

confidence: 97%

Association between thyroid profile and serum bilirubin levels in term neonates on day 3 of life

Hitender¹,

Kiran²,

Himanshu³

2020

Int. J. Paediatrics Geriatrics

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“…Penelitian oleh Sriram dan Paramahamsa (2019) di India mengatakan bahwa insiden hiperbilirubinemia lebih tinggi terjadi pada bayi laki-laki dengan persentase sebanyak 86,7%. 17 Berdasarkan kategori kadar bilirubin pada penelitian didapatkan pasien terbanyak dengan kategori high risk sebanyak 25 pasien (35,7%). Hasil penelitian ini sejalan dengan AAP dimana insidensi tertinggi neonatus yang mengalami hiperbilirubinemia adalah pada kategori high risk zone.…”

Section: Pembahasanunclassified

Gambaran Faktor Risiko Hiperbilirubinemia Pada Neonatus yang Dirawat di Ruang Perinatologi RSUP Dr. M. Djamil Padang

Fadhillah,

Afdal,

Pertiwi

et al. 2024

JIKESI

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Abstrak Latar Belakang: Hiperbilirubinemia ditandai dengan adanya ikterus. Hiperbilirubinemia dibedakan menjadi dua jenis, yaitu hiperbilirubinemia fisiologis dan patologis. Hiperbilirubinemia pada neonatus perlu mendapat perhatian karena dapat menyebabkan neonatus mengalami bilirubin ensefalopati akut atau pada fase lanjut akan menyebabkan kernikterus Objektif: Penelitian ini bertujuan untuk mengetahui gambaran faktor risiko hiperbilirubinemia pada neonatus yang dirawat di perinatologi RSUP Dr. M. Djamil Padang Metode: Penelitian ini merupakan penelitian deskriptif retrospektif yang menggunakan data rekam medis neonatus dengan hiperbilirubinemia pada bulan Januari 2021 hingga Desember 2022 Hasil: Hasil penelitian ini didapatkan 58,6% neonatus dengan hiperbilirubinemia berjenis kelamin laki-laki, dan 35,7% masuk dalam kategori high risk. Kejadian faktor risiko hiperbilrubinemia pada neonatus adalah 35,6% dengan berat lahir rendah, 32,8% dengan inkompatibilitas darah, 32,8% dengan preterm, 21,4% dengan infeksi, 7,1% dengan breastfeeding jaundice, dan 1,4% dengan ibu diabetes melitus. Tidak ditemukan faktor risiko polisitemia pada neonatus yang hiperbilirubinemia. Kesimpulan. Pada penelitian ini didapatkan faktor risiko hiperbilirubinemia pada neonatus terbanyak adalah BBLR, diikuti oleh faktor risiko lainnya seperti inkompatibilitas darah, usia gestasi, infeksi, breastfeeding jaundice, dan ibu diabetes melitus Abstract Background: Hyperbilirubinemia is an increased level of bilirubin in the blood which is clinically characterized by icterus. There are various risk factors for hyperbilirubinemia in neonates so attention needs to be paid because it can cause neonates to experience acute bilirubin encephalopathy or in the advanced phase it can cause kernicterus. Objective: This study aims to describe the risk factors for hyperbilirubinemia in neonates treated at the neonatology department of RSUP Dr. M. Djamil Padang. Method: This research is a retrospective descriptive study using medical records of neonates with hyperbilirubinemia. This research was conducted at RSUP Dr. M. Djamil Padang in January 2021 – December 2022. In this study, 70 samples were obtained from neonates with a diagnosis of hyperbilirubinemia who met the inclusion criteria. Result: The results of this study founded that 35,7% of neonates with hyperbilirubinemia were included in the high risk category. 41% of neonates with hyperbilirubinemia are male. The risk factors for hyperbilirubinemia in neonates were 35.6% with low birth weight neonates, 32.8% with blood incompatibility, 32.8% with preterm, 21.4% with infections, 7.1% with breastfeeding jaundice, and 1.4% with diabetes mellitus. No risk factors for polycythemia were found in neonates with hyperbilirubinemia. Conclusion: The conclusion of this study is the most common risk factor for hyperbilirubinemia in neonates is LBW, followed by other risk factors such as blood incompatibility, gestational age, infection, breastfeeding jaundice, cholestasis, and maternal diabetes mellitus. Keyword: Neonates, hyperbilirubinemia, risk factors.

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“…Hiperbilirubinemia biasanya normal terjadi, namun dapat berpotensi menjadi patologis (ensefalopati bilirubin) yaitu sebesar 10% (Mathindas et al, 2013;Rohsiswatmo, 2013;Suradi dan Letupeirissa, 2013). Bayi didiagnosa hiperbilirubinemia apabila memiliki nilai bilirubin total lebih dari 12 mg/dL (>205 μmol/L) saat 25-48 jam kehidupan bayi aterm dan lebih dari 10 mg/dL (>171 μmol/L) pada bayi preterm (Sulistijono dkk., 2010;Sriram and Paramahamsa, 2019). Apabila kadar bilirubin total > 20mg/dL, bilirubin mampu menembus sawar otak, akibatnya bisa berupa toksik pada sel otak (Porter & Dennis, 2002).…”

Section: Pendahuluanunclassified

The Risk Factors for the Hyperbilirubinemia Incident in Neonates at Dr. Ramelan Hospital in Surabaya

Triani¹,

Setyoboedi

Budiono³

2022

IMHSJ

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condition that often occurs in neonates. This condition is important to note, because if the bilirubin levels are too high, it can lead to several complications in the brain, such as encephalopathy and cerebral palsy in infants.Objective: The objective of this study is to analyze which maternal and neonatal risk factors can cause hyperbilirubinemia in neonates. Methods: This study is an analytical study with a cross sectional approach. Population samples was taken from the perinatology room Dr. Rumkital. Ramelan Surabaya in January 2018 - December 2019, there were 252 samples and 122 samples who experienced hyperbilirubinemia. Data analysis using Chi Square test and logistic regression. Results: It was found that the type of delivery with cesarean section was the largest percentage with a p value of 0.106;; Most LBW with p value 0.038; male at most with a p value of 0.046. From the results of multivariate analysis, it was found that the variable birth weight had a greater influence on the incidence of hyperbilirubinemia compared to other variables with a significance value of p value 0.00 on alpha 5%. Conclusion: There is a significant relationship between type of gestational age, sex and birth weight with the incidence of hyperbilirubinemia, while the type of delivery and parity have no significant relationship with the incidence of hyperbilirubinemiia. Keywords: Hyperbilirubinemia, Neonates, Risk Factor

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Predictive value of serum bilirubin level for identifying term neonates at risk for subsequent hyperbilirubinemia

Cited by 3 publications

References 12 publications

Association between thyroid profile and serum bilirubin levels in term neonates on day 3 of life

Association between thyroid profile and serum bilirubin levels in term neonates on day 3 of life

Gambaran Faktor Risiko Hiperbilirubinemia Pada Neonatus yang Dirawat di Ruang Perinatologi RSUP Dr. M. Djamil Padang

The Risk Factors for the Hyperbilirubinemia Incident in Neonates at Dr. Ramelan Hospital in Surabaya

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