Predictive Value and Efficiency of Laboratory Testing

Galen, Robert S.

doi:10.1016/s0031-3955(16)33930-x

Cited by 141 publications

(74 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The sensitivity, specificity, and accuracy of the ELISA when compared with the specimen culture method were 92.45, 97.5, and 96.59%, respectively (8). The sensitivity of the ELISA in this study was higher than those reported by Kaufman et al (11,12).…”

contrasting

confidence: 62%

Antigen Detection Assay for Identification ofPenicillium marneffeiInfection

et al. 2003

View full text Add to dashboard Cite

show abstract

contrasting

confidence: 62%

Antigen Detection Assay for Identification ofPenicillium marneffeiInfection

et al. 2003

View full text Add to dashboard Cite

show abstract

“…The diagnostic sensitivity, specificity, accuracy, and predictive values were calculated and expressed using a standard method. 25 The sensitivity of two different methods was compared by using McNemar's χ 2 test.…”

Section: Real-time Fret Pcrmentioning

confidence: 99%

Rapid Molecular Detection of Opisthorchis viverrini in Human Fecal Samples by Real-Time Polymerase Chain Reaction

Intapan

Thanchomnang²,

Lulitanond³

et al. 2009

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

Abstract. Real-time fluorescence resonance energy transfer (FRET) polymerase chain reaction (PCR) supplemented with melting curve analysis is a highly sensitive and fast method offering a high throughput. We report the development of a real-time FRET PCR for molecular detection of Opisthorchis viverrini in human fecal samples. The diagnostic sensitivity, specificity, accuracy, and positive and negative predictive values of this method were 97.5%, 100%, 98.9%, 100%, and 98.2%, respectively. The sensitivity was not significantly different from that of the quantified formalin-ethyl acetate concentration technique, the gold standard ( P > 0.05). The procedure has potential for diagnosis of human opisthorchiasis in disease-endemic areas, for large epidemiologic investigations involving at risk populations, and monitoring eradication programs of the liver fluke, which causes hepatobiliary diseases and induces cholangiocarcinoma.

show abstract

“…Sensitivity and specificity of the tests were determined using the method of Galen (1980) . Association between GPAT and ELISA was evaluated using linear correlation and regression after the titers of GPAT were transformed into logarithm (log2) .…”

Section: Discussionmentioning

confidence: 99%

Detection of antibodies to Parastrongylus cantonensis in human sera by gelatin particle indirect agglutination test.

Eamsobhana

Watthanakulpanich

Punthuprapasa

et al. 1999

Jap. J. Trop. Med. Hyg.

View full text Add to dashboard Cite

Abstract:A newly developed agglutination test using gelatin particles as an antigen carrier (GPAT) was compared with a conventional enzyme-linked immunosorbent assay (ELISA) for the detection of Parastrongylus cantonensis antibodies in sera from patients. A total of 70 sera was used in the study. Of these, 10 each were from patients with parastrongyliasis, gnathostomiasis, paragonimiasis, cysticercosis, toxocariasis, filariasis and malaria.The control group consisted of 50 serum samples from normal healthy individuals. The mean reciprocal titer of the parastrongyliasis patients group was significantly higher than that of the normal group as well as those of other parasitic infections. The sensitivity and specificity of the GPAT were 100% and 92.4%, respectively. The results of GPAT in detecting P. cantonensis antibodies appeared to be closely correlated with those obtained with ELISA. The GPAT, however, is more easy, rapid and cheap; it may also be a test of choice for routine immunodiagnosis of human parastrongyliasis.

show abstract

Predictive Value and Efficiency of Laboratory Testing

Cited by 141 publications

References 10 publications

Antigen Detection Assay for Identification ofPenicillium marneffeiInfection

Antigen Detection Assay for Identification ofPenicillium marneffeiInfection

Rapid Molecular Detection of Opisthorchis viverrini in Human Fecal Samples by Real-Time Polymerase Chain Reaction

Detection of antibodies to Parastrongylus cantonensis in human sera by gelatin particle indirect agglutination test.

Contact Info

Product

Resources

About