Predictive Factors for Vesicoureteral Reflux and Prenatally Diagnosed Renal Pelvic Dilatation

Abstract

Fetal and postnatal renal pelvic dilatation was a poor predictor of vesicoureteral reflux. Nevertheless, diagnostic accuracy regarding clinically significant vesicoureteral reflux improved when fetal and postnatal renal pelvic dilatation less than 10 mm was considered a negative indicator of reflux.

Combined Use of Late Phase Dimercapto-Succinic Acid Renal Scintigraphy and Ultrasound as First Line Screening After Urinary Tract Infection in Children

“…[22][23][24] Nevertheless, in a prospective study of infants with prenatal hydronephrosis Dias et al observed that there was an improvement in the diagnostic accuracy of high grade VUR when fetal and postnatal renal pelvic diameters were greater than 10 mm. 25 In the present study the diagnostic accuracy of US for detecting dilating vesicoureteral reflux was similar to that of DMSA scan (83.3%) but with lower specificity (61.2%) and diagnostic OR (7.9). Recent studies have revealed inconsistent findings regarding the role of US for evaluation of UTI in children.…”

Early risk factors for neonatal mortality in CAKUT: analysis of 524 affected newborns

“…In 1989, we established a multidisciplinary program with the aim of providing prenatal diagnoses, specialized clinical management, and follow-up for patients with CAKUT. Since the beginning, we have studied several aspects of these abnormalities [2,14,21,22,24,25,32,33]. Therefore, it was not surprising that our prevalence rate is about tenfold greater than those reported in other epidemiological studies.…”

“…Congenital abnormalities of the kidney and urinary tract (CAKUT) is a significant cause of morbidity and mortality in children [1][2][3][4][5][6][7][8]. CAKUT is the most common cause of pediatric end-stage renal disease, accounting for approximately 50% of all cases [9][10][11][12].…”

The outcome of antenatal ultrasound diagnosed anomalies of the kidney and urinary tract in a large Danish birth cohort

“…Another study found that only 2% had fUTI and 1% had surgery if postnatal APD was 5–14 mm 33. No threshold was given by Dias et al ,34 35 even though they reported that postnatal APD was better for detecting the need of pyleoplasty than the Society for Fetal Urology grading system,35 and that risk of dilated VUR increased with postnatal APD >10 mm 34. According to our criteria for performing VCUG, some VUR cases without dilated ureters on US, no fUTI and normal kidney function may be classified as hydronephrosis in our study.…”