Predicting the different progressions of early pressure injury by ultraviolet photography in rat models

Abstract

Early pressure injury (PI) can result in either spontaneous healing (SH) or deterioration into ulcer (DU). However, determining whether PI will progress into SH or DU on the basis of non-blanchable erythema only is difficult. In this study, we constructed two animal PI models to mimic SH and DU injuries and observed haemorrhage by using ultraviolet (UV) photography to develop potential clinical indicators for predicting the progression of early PI. Macroscopy, UV photography, and skin temperature observations were obtained. In the SH group, macroscopic observation showed the erythema was obvious at 0.5 hours after decompression and faded gradually had almost disappeared at 72 hours. In the DU group, the erythema persisted, and an erosion appeared at 24 hours after decompression and expanded at 36 hours. The erythema developed into an obvious ulcer at 48 hours and enlarged at 72 hours. The obvious ulcer found at 48 hours through macroscopic observation was clearly visible at 36 hours with UV photography, and a significant difference in grey values between the two groups was found at as early as 18 hours (P < .05). This study provided evidence showing that UV photography can predict the different progression stages of early PI. Additionally, when combined with the transparent disc method, UV photography also can be used to identify the circulatory disorders of early PI, such as haemorrhage or hyperaemia and even congestion.circulatory disorders, early pressure injury, erythema, predicting progression, ultraviolet Key Messages• the principle of Hb absorption of UV is used to provide evidence of haemorrhage in the skin to predict the different progression of early PI. The combination of UV photography and the transparent disc method could Huiwen Xu and Yanwei Wang contributed equally to this work.

Elucidation of Ischemic Mechanisms of Early Pressure Injury during Post-Decompression and Detecting Methods

“…For example, the degree of erythema in early PI was rather lighter than in BE [ 8 ]. Our previous study found that this may be attributable to the fact that the erythema in early PI is a mixed lesion of multiple circulatory disturbances (e.g., hyperemia, congestion, and hemorrhage) [ 15 ]. Therefore, the erythema becomes more severe than the simple congestion of BE.…”

“…The CRTT was implemented using the transparent disc method. According to the method of a previous study [ 15 ], the pressure applied in the CRTT in the current study was set at 150 mmHg.…”

Effect of Heat Shock Preconditioning on Pressure Injury Prevention via Hsp27 Upregulation in Rat Models

“…The PI rat model was adopted using magnetic compression focusing on I/R injury for the formation of skin ulcerations [ 66 , 67 ]. PI rat models were developed as described in a previous study [ 68 ]. The dorsal skin was gently pulled up and placed between 2 round magnetic disks measuring 10 mm and 3 mm in diameter and thickness respectively, with an average of 3000 Gauss magnetic force (NE05, Niroku Seisakusho Co., Ltd., Kobe, Japan).…”

Portable Skin-injury Monitoring Device for Early Diagnosis of Pressure Ulcers

“…A simple prototype has been fabricated in a previous study where the UV brightness could be adjusted; however, the prototype lacked features such as pressure feedback, real-time monitoring, and a camera function. (16) In this study, we have designed a new portable monitoring device, which can quantitatively record the pressure from the diascope, precisely adjust the brightness of UV light and white light, and most importantly observe the patient's skin surface in real time and take high-quality photos for analysis. Figure 1 shows the portable skin-injury monitoring device and the major components within the measurement unit.…”