2023
DOI: 10.1093/molehr/gaad002
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Preconception paternal alcohol exposure decreases IVF embryo survival and pregnancy success rates in a mouse model

Abstract: Increasingly, couples struggling with fertility turn to assisted reproductive techniques, including in vitro fertilization (IVF), to have children. Despite the demonstrated influence of periconception male health and lifestyle choices on offspring development, studies examining IVF success rates and child health outcomes remain exclusively focused on maternal factors. Using a physiologically relevant mouse model, we tested the hypothesis that chronic paternal preconception alcohol intake adversely affects IVF … Show more

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