Prealbumin as a Marker for Carcinoid Tumours

Reid, W. A.; Miller, Iain D.; Liddle, C N; Horne, C. H. W.

doi:10.1016/b978-0-08-030764-0.50086-0

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…Mineralogical analysis of ore and plant stream samples performed by scanning electron microscopy, uses a sample of order 10-1000 µm particles of narrow size range that are mounted in a resin block. The LEO QEMSCAN system developed by CSIRO Minerals (Miller et al, 1982;Reid et al, 1984) identifies minerals by analysis of energy dispersive xray (EDX) spectrum and backscattered electron intensity (BEI) from polished single sections of particles. Liberation measurements estimate the volumetric grade distribution of a mineral as a measure of the quality in a processing stream.…”

Section: Introductionmentioning

confidence: 99%

Stereological Correction of Mineral Liberation Grade Distributions Estimated by Single Sectioning of Particles

Spencer¹,

Sutherland²

2011

Image Anal Stereol

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The liberation distribution of ore samples is of considerable interest for process optimisation in the minerals industry. A scanning electron microscope-based automatic mineral analyser such as the LEO QEMSCAN system developed by CSIRO Minerals is a powerful tool for the estimation of linear or areal grade distributions of a population of ore particles based upon polished single particle sections. Stereological correction of a single section mineralogical grade distribution is recognised as an ill-posed inverse problem. The transformation kernel method with constrained entropy regularisation (King and Schneider, 1998) is adopted for the correction of stereological error in binary systems. An enhanced transformation kernel correction scheme is developed with an additional equality constraint for average grade as determined by section and volumetric sampling, in accordance with Delesse's fundamental stereological theorem. The usefulness of both correction methods is limited by the availability of kernels that appropriately model the relationship between volumetric and section grade distributions for the mineralogical sample of interest. The transformation kernel stereological correction methods are implemented in software available for use as part of the LEO QEMSCAN system. Both correction procedures are applied to areal section grade distributions of feed and concentrate from a mineral processing plant. The corrected grade distributions are in some instances found to be sensitive to the application of the average grade constraint. The statistical significance of differences in the corrected solutions is discussed

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Section: Introductionmentioning

confidence: 99%

Stereological Correction of Mineral Liberation Grade Distributions Estimated by Single Sectioning of Particles

Spencer¹,

Sutherland²

2011

Image Anal Stereol

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Immunolocalization of prealbumin as a marker for carcinoid tumours

Miller

Reid

Liddle

et al. 1984

The Journal of Pathology

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Using a PAP immunoperoxidase technique, we have demonstrated the plasma protein prealbumin in 92 (87 per cent) out of a series of 106 carcinoid tumours from various sites. The frequency of detection was greater than with the conventional stains; 83 (78 per cent) of the cases were positive for one or more of these stains. The Grimelius technique was by far the most effective of the conventional stains; it was positive in 81 (76 per cent) cases. We were unable to detect prealbumin in a variety of carcinomas. Although prealbumin identification did not appear to have any advantage over the routine stains in midgut-derived carcinoids, it was much more effective in the diagnosis of bronchial (foregut) and rectal (hindgut) carcinoids. We believe that prealbumin staining offers a cheap, reliable and valuable method for the detection of carcinoid tumours in routine histopathology.

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Prealbumin as a Marker for Carcinoid Tumours

Cited by 2 publications

References 9 publications

Stereological Correction of Mineral Liberation Grade Distributions Estimated by Single Sectioning of Particles

Stereological Correction of Mineral Liberation Grade Distributions Estimated by Single Sectioning of Particles

Immunolocalization of prealbumin as a marker for carcinoid tumours

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