Practices related to late-onset sepsis in very low-birth weight preterm infants

Bentlin, Maria Regina; Rugolo, Lígia M. S. S.; Ferrari, Lígia S L

doi:10.1016/j.jped.2014.07.004

Cited by 17 publications

(3 citation statements)

References 19 publications

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“…23 A multicenter study conducted by the RBPN between 2009 and 2010 showed 50% of late sepsis in premature infants <1500 g ranging from 29 to 72% between centers, with 27% accounting for confirmed late sepsis and 23%, clinical sepsis. 24 A RBPN cohort study on premature infants <1500 g, conducted between 2006 and 2008, also showed that late sepsis is common in premature infants <1500 g, with an incidence of 24% for sepsis confirmed with blood culture, and is associated with higher mortality. 25 A cohort study performed in Spain between 2006 and 2012 on newborns <30 weeks and/or <1500 g verified a 17.2% incidence of sepsis.…”

Section: Discussionmentioning

confidence: 99%

Snappe Ii: Analysis of Accuracy and Determination of the Cutoff Point as a Death Predictor in a Brazilian Neonatal Intensive Care Unit

Fontenele

Silva

Leite

et al. 2020

Rev. paul. pediatr.

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Objective: To analyze the accuracy of the Score for Neonatal Acute Physiology Perinatal Extension (SNAPPE II) as a death predictor, to determine the cutoff point for mortality, and to analyze the association of independent variables with death. Methods: Prospective, longitudinal, hospital-based study on newborns admitted to the Neonatal Intensive Care Unit (NICU) for the first time from November 1, 2016 to April 30, 2017. Newborns with less than 12 hours of length of stay at the NICU, out-of-hospital births, major congenital malformations, and inter-hospital transfer were excluded. Variables were grouped according to hierarchical framework, related to maternal characteristics (distal level), prenatal and childbirth care (intermediate level), and birth conditions (proximal level). Descriptive analyses of SNAPPE II score ranges, Receiver Operating Characteristics Curve (ROC curve) to define the cutoff point for mortality, and bivariate analysis by the Wald test and multiple logistic regression were conducted. Results: After selection, the sample consisted of 247 newborns. In this study, the SNAPPE II cutoff point for mortality was 27, with sensitivity of 84.1% and specificity of 82.4%. 61% of those with a score ≥27 died. Multiple logistic regression showed an association between death and proximal-level variables: sepsis (Odds Ratio [OR] 10.68; 95% confidence interval [95%CI] 2.82–40.48; p<0.001); SNAPPE II ≥27 (OR 5.85; 95%CI 1.90–18.05; p=0.002); birth weight 750–999 g (OR 4.15; 95%CI 1.06–16.14; p=0.040); and nonuse of surfactant (OR 0.159; 95%CI 0.04–0.53; p=0.003). Conclusions: Neonatal mortality was directly proportional to increase in SNAPPE II. Score≥27 increased the odds of dying by six times compared with neonates with lower scores. The proximal variables related to health conditions and neonatal care were associated with death.

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Section: Discussionmentioning

confidence: 99%

Snappe Ii: Analysis of Accuracy and Determination of the Cutoff Point as a Death Predictor in a Brazilian Neonatal Intensive Care Unit

Fontenele

Silva

Leite

et al. 2020

Rev. paul. pediatr.

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“…Although there is resistance to oxacillin in many neonatal units, the administration of this drug associated with amikacin was effective in saving the CVC in 13 cases of CRBSI. Brazilian studies prove the efficacy of anti-staphylococcal β lactam to treat CRBSIs (33,38) .…”

Section: Discussionmentioning

confidence: 99%

Prevalence of central venous catheter salvage in newborn with staphylococcal bloodstream infection

et al. 2021

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Objectives: to establish the prevalence of salvage of central venous catheters in newborns with bloodstream infection caused by coagulase-negative staphylococci. Methods: retrospective cross-sectional study with 136 newborns admitted to the Neonatal Intensive Care Unit between 2011 and 2017. The total of 143 infection events undergoing antibiotic therapy were evaluated. Results: among the 143 infection events, 39 catheters in which antibiotic therapy was used were saved and in 69 cases, the device was removed. Positive central blood culture and single lumen catheter were factors associated with salvage failure. The probability of salvage decreased with infections diagnosed from 15 days of using the catheter. Negative blood culture raised the chance of salvage by fourfold. Conclusions: the use of antibiotic therapy in the treatment of infections resulted in a low prevalence of salvage of the central venous catheter. The probability of salvage was associated with variables of the device.

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“…De modo geral, os três hospitais avaliaram de forma positiva a retirada de adornos, trazendo um percentual elevado da prática de diminuição do risco de infecção, do conhecimento dos protocolos e, consequentemente, de uma cirurgia mais segura [12].…”

Section: Discussionunclassified

Conhecimentos, atitudes e práticas sobre cirurgia segura entre profissionais do bloco operatório

Pereira¹,

Brito²,

Ferreira³

et al. 2019

Enferm Bras

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Introdução: A temática da cirurgia segura é relevante para a prevenção de erros relacionados à assistência à saúde e deve ser sempre valorizada e motivo de atenção dos profissionais do bloco operatório. Objetivo: Identificar o conhecimento, atitudes e práticas da equipe multidisciplinar do bloco operatório sobre cirurgia segura baseada no uso da lista de verificação. Métodos: Trata-se de um estudo transversal, de característica descritiva, desenvolvido a partir do inquérito denominado CAP (Conhecimentos, Atitudes e Práticas em saúde), com análise quantitativa dos dados. A amostra foi composta por 117 profissionais, entre médicos, enfermeiros e técnicos de enfermagem, que atuam no bloco operatório de três hospitais da cidade de Recife/PE. Os dados foram coletados por meio de um formulário semiestruturado. Resultados: O conhecimento, atitudes e práticas dos profissionais foram semelhantes nos três hospitais estudados, que apresentaram bons resultados, apesar do hospital C apresentar resultados inferiores aos hospitais A e B. Conclusão: Os profissionais dos hospitais analisados apresentaram-se de forma positiva quanto à compreensão e importância da cirurgia segura, porém observou-se uma omissão por parte de alguns profissionais do nível técnico quanto a algumas questões sobre o protocolo, apresentando a necessidade de uma capacitação profissional e abrangência do conhecimento sobre o tema.Palavras-chave: segurança do paciente, prática profissional, centros cirúrgicos, conhecimento.

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Practices related to late-onset sepsis in very low-birth weight preterm infants

Abstract: The knowledge of the practices of each center allowed for the identification of aspects to be improved as a strategy to reduce LOS, including: alcohol gel use, hand hygiene training, implementation of catheter teams, and wise use of antibiotic therapy.

Cited by 17 publications

References 19 publications

Snappe Ii: Analysis of Accuracy and Determination of the Cutoff Point as a Death Predictor in a Brazilian Neonatal Intensive Care Unit

Snappe Ii: Analysis of Accuracy and Determination of the Cutoff Point as a Death Predictor in a Brazilian Neonatal Intensive Care Unit

Prevalence of central venous catheter salvage in newborn with staphylococcal bloodstream infection

Conhecimentos, atitudes e práticas sobre cirurgia segura entre profissionais do bloco operatório

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