PP-75. Mean platelet volume in very preterm infants: A predictor of morbidities?

Background: Since the intraventricular hemorrhage (IVH) is still a serious problem in premature infants associated with poor neurodevelopmental outcomes, there is a need for an accessible tool in order to identify these at high risk neonates. Objectives: To determine if high mean platelet volume (MPV) within 24 hours of birth can identify preterm infants prone to IVH as a simple accessible test. Methods: One hundred premature infants with gestational age (GA) of < 34 weeks with respiratory distress syndrome (RDS) were eligible in this study and were divided into two groups based on the diagnosis of IVH. Measurements of MPV and platelet counts

show abstract

“…This was also studied by Cekmez et al (28) and Bolouki Moghaddam et al (20). Unlike their results we found this correlated with higher MPV.…”

Section: Discussionmentioning

confidence: 58%

Mean Platelet Volume as a Marker of Intraventricular Hemorrhage in Very Premature Infants

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Cekmez et al found there were no statistically significant differences in MPV values between infants with ROP and controls [13]. We noticed that the blood samples were drawn in the first 2 hours of an infants' life in their study.…”

Section: Discussionmentioning

confidence: 72%

Relationship between mean platelet volume and retinopathy of prematurity

Tao

Dong

et al. 2015

Graefes Arch Clin Exp Ophthalmol

View full text Add to dashboard Cite

show abstract

“…Neonates with RDS and late‐onset pneumonia had higher MPV . MPV in early postnatal life is higher in premature infants with bronchopulmonary dysplasia than in infants without this disease . In contrast, Karadag‐Oncel et al .…”

Section: Discussionmentioning

confidence: 88%

Platelet mass index and prediction of severity of transient tachypnea of the newborn

İlhan

Bor

2019

Pediatrics International

View full text Add to dashboard Cite

Background Platelet mass index (PMI) is associated with platelet functionality. The aim of this study was to evaluate the role of PMI in predicting the severity of transient tachypnea of the newborn (TTN). Methods Infants with gestational age ≥37 weeks and birthweight ≥2,000 g who were given nasal intermittent mandatory ventilation for TTN ≤6 h after birth were retrospectively enrolled in this study. PMI was calculated using the following formula: PMI = platelet count × mean platelet volume/103 (fL/nL). The study infants (n = 101) were divided into two groups according to the duration of tachypnea: ≤48 h (n = 45) and >48 h (n = 56). Results The PMI and platelet count were significantly lower in the group with tachypnea duration >48 h than in the tachypnea duration ≤48 h group (P < 0.001 and P = 0.04, respectively). A negative significant correlation was noted between PMI and the duration of tachypnea (r = −0.43, P < 0.001). A PMI cut‐off of 1,562 fL/nL can predict prolonged tachypnea (>48 h) with a sensitivity of 62.5%, specificity of 68.9%, positive predictive value of 71.4%, and negative predictive value of 59.6% (area under the curve, 0.682 ± 0.053; P = 0.002). Conclusions Lower PMI and lower platelet count are associated with longer duration of tachypnea in patients with TTN.

show abstract

PP-75. Mean platelet volume in very preterm infants: A predictor of morbidities?

Cited by 41 publications

References 0 publications

Mean Platelet Volume as a Marker of Intraventricular Hemorrhage in Very Premature Infants

Mean Platelet Volume as a Marker of Intraventricular Hemorrhage in Very Premature Infants

Relationship between mean platelet volume and retinopathy of prematurity

Platelet mass index and prediction of severity of transient tachypnea of the newborn

Contact Info

Product

Resources

About