Potential use of Liquid Membranes for Emergency Treatment of Drug Overdose

A new solution to emulsion liquid membrane problems by non‐Newtonian conversion

“…This stabilizing effect of increased " viscosity" results from increased resistance to globule deformation and membrane breakage by pressure and shearing forces, and is in accordance with the findings of Frankenfeld et al (1976), Yang and Rhodes (1980), Terry et al (19821, and Calabrese et al (1986).…”

Effects of Osmotic Pressure on Water Transport in W1/O/W2 Emulsions

“…Control of the osmotic-pressure-driven water migration between the suspending (W 2 ) and the entrapped (W 1 ) aqueous phases of W 1 /O/W 2 emulsions is critical in various diverse fields such as the food industry (1), agricultural formulations (2), red blood substitutes (3,4), separation processes (5-7), cosmetics (8), pharmaceuticals (9)(10)(11), etc. Such water transport has been reported to be affected by the magnitude of the osmotic pressure gradients between phases W 1 and W 2 , the nature and concentrations of the surfactants used for the preparation of the emulsions, and the nature and viscosity of the oil phase (12)(13)(14)(15)(16)(17).…”

Potential of liquid membranes for drug overdose treatment: In vitro studies

“…They also may have potential as an emergency treatment of a drug overdose (7). Preliminary in vitro studies indicated that liquid membranes were capable of rapid uptake of phenobarbital and aspirin from either pH 2 or 7 buffered donor solutions (7).…”

“…They also may have potential as an emergency treatment of a drug overdose (7). Preliminary in vitro studies indicated that liquid membranes were capable of rapid uptake of phenobarbital and aspirin from either pH 2 or 7 buffered donor solutions (7). To understand the properties of liquid membranes in drug overdose treatment, in uitro studies were conducted under different temperatures and phase ratios of liquid membranes to the donor solutions.…”