Potential of a novel polyherbal formulation BASANT for prevention of Chlamydia trachomatis infection

A novel polyherbal microbicide with inhibitory effect on bacterial, fungal and viral genital pathogens

“…Basant was effective against all standard strains and clinical isolates of C. albicans and C. glabrata tested, including those resistant to azole drugs and amphotericin B. Besides Candida, Basant has also shown pre-and post-infection inhibitory effect on C. trachomatis [15].…”

An antimicrobial investigation of plants used traditionally in southern Africa to treat sexually transmitted infections

“…On reviewing the ethnobotanical literature pertaining to medicinal plants of southern Africa, over 80 references to STI therapy could be found (Watt and Breyer-Brandwijk, 1962;Hutchings et al, 1996;Neuwinger et al, 2000;Von Koenen, 2001). Some plant-based antimicrobial studies with STI relevance have been undertaken (Talwar et al, 2000;Vermani and Garg, 2002;Okoli and Iroegbu, 2004;Schwiertz et al, 2006;Bhengraj et al, 2008;Shokeen et al, 2009); however, only a few have been undertaken on indigenous South African medicinal plants (Kambizi et al, 2004;Tshikalange et al, 2005;Buwa and Van Staden, 2006;Tsikalange et al, 2008;Klos et al, 2009). These studies have shown antimicrobial efficacy, but have not been tested on bacterial pathogens associated with STI's.…”

BASANT, a Polyherbal Safe Microbicide Eliminates HPV-16 in Women with Early Cervical Intraepithelial Lesions

“…It has pronounced inhibitory action against Candida glabrata, Candida albicans and Candida tropicalis isolated from women with vulvovaginal candidiasis, including three isolates resistant to azole drugs and amphotericin [4]. It exercises also inhibitory action on free as well as cell-infected Chlamydia trachomatis [5]. It prevents the entry of HPV 16 in Hela cells 4 .…”