An antimicrobial investigation of plants used traditionally in southern Africa to treat sexually transmitted infections

Vuuren, Sandy van; Naidoo, Dinesh

doi:10.1016/j.jep.2010.05.045

Cited by 98 publications

(60 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Even though the aqueous extract preparation aimed to mimic the traditional use, very little noteworthy antimicrobial activity was observed. These findings correlate with that found previously where aqueous extracts showed low or no antimicrobial activity (Shale et al, 1999;Bamuamba et al, 2008;Van Vuuren and Naidoo, 2010;Kariuki and Njoroge, 2011). Shale et al (1999) specifically suggested that water is not the most effectual solvent for extracting the active compounds from plants.…”

Section: Discussionsupporting

confidence: 90%

An antimicrobial evaluation of plants used for the treatment of respiratory infections in rural Maputaland, KwaZulu-Natal, South Africa

York

Vuuren

Wet

2012

Journal of Ethnopharmacology

Self Cite

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 90%

An antimicrobial evaluation of plants used for the treatment of respiratory infections in rural Maputaland, KwaZulu-Natal, South Africa

York

Vuuren

Wet

2012

Journal of Ethnopharmacology

Self Cite

View full text Add to dashboard Cite

“…Gastro-intestinal disorders, particularly cholera, diarrhoea and dysentery are a major concern not only in south-central Zimbabwe but the whole country and; in Mozambique as well, where dysentery and cholera usually result in high mortality rate if not treated promptly [142]. Sexually transmitted infections are a major public health concern in developing countries with their transmission rate regarded as one of the highest in the world [143]. Sexually transmitted infections are one of the most common reasons for people to use herbal medicines and visit traditional healers in Zimbabwe [1,4,8].…”

Section: Methodsmentioning

confidence: 99%

Traditional use of medicinal plants in south-central Zimbabwe: review and perspectives

Maroyi

2013

J Ethnobiology Ethnomedicine

286

174

View full text Add to dashboard Cite

BackgroundTraditional medicine has remained as the most affordable and easily accessible source of treatment in the primary healthcare system of resource poor communities in Zimbabwe. The local people have a long history of traditional plant usage for medicinal purposes. Despite the increasing acceptance of traditional medicine in Zimbabwe, this rich indigenous knowledge is not adequately documented. Documentation of plants used as traditional medicines is needed so that the knowledge can be preserved and the utilized plants conserved and used sustainably. The primary objective of this paper is to summarize information on traditional uses of medicinal plants in south-central Zimbabwe, identifying research gaps and suggesting perspectives for future research.MethodsThis study is based on a review of the literature published in scientific journals, books, reports from national, regional and international organizations, theses, conference papers and other grey materials.ResultsA total of 93 medicinal plant species representing 41 families and 77 genera are used in south-central Zimbabwe. These plant species are used to treat 18 diseases and disorder categories, with the highest number of species used for gastro-intestinal disorders, followed by sexually transmitted infections, cold, cough and sore throat and gynaecological problems. Shrubs and trees (38% each) were the primary sources of medicinal plants, followed by herbs (21%) and climbers (3%). The therapeutic claims made on medicinal plants documented in south-central Zimbabwe are well supported by literature, with 82.8% of the plant species having similar applications in other regions of Zimbabwe as well as other parts of the world and 89.2% having documented biological and pharmacological properties.ConclusionThis study illustrates the importance of traditional medicines in the treatment and management of human diseases and ailments in south-central Zimbabwe. Traditional medicines still play an important role in meeting basic health care of local communities in Zimbabwe.

show abstract

“…MICs were determined by the agar-dilution method based on the Clinical and Laboratory Standards Institute guidelines [6,8]. Each essential oil was diluted in sterile 0.15% agar solution [9].…”

Section: Methodsmentioning

confidence: 99%

“…For example, MRSA is susceptible to thyme white oil, lemon oil, lemongrass oil, and cinnamon oil [7]. The susceptibility of STIs to essential oils is not well studied, although Neisseria gonorrhoeae is susceptible to the essential oil of Croton gratissimus [8]. …”

Section: Introductionmentioning

confidence: 99%

Assessing the antibiotic potential of essential oils against Haemophilus ducreyi

Lindeman

Waggoner

Batdorff

et al. 2014

BMC Complement Altern Med

View full text Add to dashboard Cite

BackgroundHaemophilus ducreyi is the bacterium responsible for the genital ulcer disease chancroid, a cofactor for the transmission of HIV, and it is resistant to many antibiotics. With the goal of exploring possible alternative treatments, we tested essential oils (EOs) for their efficacy as antimicrobial agents against H. ducreyi.MethodsWe determine the minimum inhibitory concentration (MIC) of Cinnamomum verum (cinnamon), Eugenia caryophyllus (clove) and Thymus satureioides (thyme) oil against 9 strains of H. ducreyi using the agar dilution method. We also determined the minimum lethal concentration for each oil by subculturing from the MIC plates onto fresh agar without essential oil. For both tests, we used a 2-way ANOVA to evaluate whether antibiotic-resistant strains had a different sensitivity to the oils relative to non-resistant strains.ResultsAll 3 oils demonstrated excellent activity against H. ducreyi, with MICs of 0.05 to 0.52 mg/mL and MLCs of 0.1-0.5 mg/mL. Antibiotic-resistant strains of H. ducreyi were equally susceptible to these 3 essential oils relative to non-resistant strains (p = 0.409).ConclusionE. caryophyllus, C. verum and T. satureioides oils are promising alternatives to antibiotic treatment for chancroid.

show abstract

An antimicrobial investigation of plants used traditionally in southern Africa to treat sexually transmitted infections

Cited by 98 publications

References 32 publications

An antimicrobial evaluation of plants used for the treatment of respiratory infections in rural Maputaland, KwaZulu-Natal, South Africa

An antimicrobial evaluation of plants used for the treatment of respiratory infections in rural Maputaland, KwaZulu-Natal, South Africa

Traditional use of medicinal plants in south-central Zimbabwe: review and perspectives

Assessing the antibiotic potential of essential oils against Haemophilus ducreyi

Contact Info

Product

Resources

About