Postoperative Antibiotic Care after Functional Endoscopic Sinus Surgery

Abstract

This study showed that postoperative care with amoxicillin/clavulante did not improve the short-term outcome of FESS on chronic rhinosinusitis or decrease bacterial growth 3weeks after FESS, although the long-term influence was not evaluated in this study.

Quality of life improvement from sinus surgery in chronic rhinosinusitis patients with asthma and nasal polyps

“…As shown in Table 1, the mean ± SD age of this overall study population was 48.43 ± 13.34 years old; 57.49% were male (n = 215); 89.43% were white (n = 330); and 7.86% were black (n = 29). The clinically significant change of SNOT-22 score was defined as difference of at least 0.5 SD of the baseline SNOT-22 score in patients without asthma and NP 16,17 ; ie, 10.6. The prevalence of allergic rhinitis and Samter's triad were significantly higher in CRS patients with asthma and NP compared to patients without asthma and NP.…”

“…Higher scores represent worse QOL. Clinically significant change of SNOT-22 score was defined as a difference of at least 0.5 standard deviations (SDs) of the baseline SNOT-22 score in the reference group, 15,16 which is the group of patients without asthma and NP in our study.…”

Oral Antibiotics as Anti-infectives

“…However, the treatment course was limited to just 2 days of cefuroxime. In another study, amoxicillin/clavulanate was compared to a control group for 3 weeks following ESS [ 16 ]. No differences in rates of positive bacterial culture, symptom scores, or endoscopic scores were noted.…”

The role of antibiotics in endoscopic sinus surgery

“…In 2008, Jiang et al [16] demonstrated no short-term benefit in either symptom or endoscopic scores to postoperative amoxicillin/ clavulanate therapy at 3 weeks. Three years later, Liang et al [17] showed that there was no difference amongst patients treated with Chinese herbal medicine, amoxicillin, or placebo in the postoperative period in the Chinese version of the Rhinosinusitis Outcome Measure (CRSOM-31) and endoscopic scores.…”