2015
DOI: 10.1097/moo.0000000000000122
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The role of antibiotics in endoscopic sinus surgery

Abstract: Purpose of reviewTo review and discuss recent literature regarding the use of antibiotics in relation to endoscopic sinus surgery (ESS), including perioperative antibiotics, postoperative antibiotics, and antibiotic usage in the setting of postoperative packing. Recent findingsPerioperative antibiotics are not recommended by the American Society of Health-System Pharmacists. The necessity of antibiotics following ESS is a heavily debated topic. Most studies show little to no improvement in outcomes. Significan… Show more

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Cited by 9 publications
(12 citation statements)
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“…toxic shock syndrome, but this remains an extremely rare complication. 30,34 That the majority of our respondents prescribed antibiotics when packing was placed is suggestive of this ongoing concern.…”
Section: Discussionmentioning
confidence: 90%
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“…toxic shock syndrome, but this remains an extremely rare complication. 30,34 That the majority of our respondents prescribed antibiotics when packing was placed is suggestive of this ongoing concern.…”
Section: Discussionmentioning
confidence: 90%
“…The majority of our respondents utilized a regimen consistent with these recommendations. Similarly, limited data exist to suggest a definitive postoperative antibiotic regimen in the setting of nasal packing placement following endoscopic sinus surgery or ESBS . Antibiotics have been prescribed in this situation for fear of toxic shock syndrome, but this remains an extremely rare complication .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Grade B evidence exists for the use of postoperative oral antibiotics to improve symptom and endoscopic scores in the first few weeks after ESS; however, these findings are temporary, and in controlled studies, there was no difference in outcome between treated and nontreated cohorts after 6 months. 41 Likewise, postoperative oral corticosteroids have been shown to improve endoscopic outcomes but only in the early postoperative period. In an evidence-based review by Rudmik and Smith, 42 a recommendation was made for early saline irrigations, topical steroid sprays, and debridement, whereas oral antibiotics and steroids, steroid-impregnated saline irrigations, and drug-eluting stents were considered optional.…”
Section: Postoperative Phasementioning
confidence: 99%
“…The theoretical benefits of antibiotic use perioperatively, namely a reduction in infection risk, improvement in patient‐reported symptoms, and enhanced surgical site healing, must be weighed against the potential risks of antibiotics. These risks include the development of antimicrobial resistance, allergic reactions, and gastrointestinal sequelae, a known cost burden on the healthcare system, and a theoretical alteration of the sinonasal microbiome that may affect disease progression …”
mentioning
confidence: 99%