Quality of life improvement from sinus surgery in chronic rhinosinusitis patients with asthma and nasal polyps

Zhang, Zi; Adappa, Nithin D.; Doghramji, Laurel; Chiu, Alexander G.; Lautenbach, Ebbing; Cohen, Noam A.; Palmer, James N.

doi:10.1002/alr.21406

Cited by 45 publications

(43 citation statements)

References 25 publications

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“…The same authors recently followed a cohort of CRSwNP patients after ESS and found an improvement in asthma symptoms score, daily peak expiratory flow, and nasal inspiratory flow. 867 Zhang et al 868 observed in their retrospective analysis that patients with both NP and asthma experience a larger QoL improvement measured by SNOT-22 at 1 and 3 months, when compared to patients without asthma or NPs. In a smaller series of patients with NP, ESS did not affect the asthma state.…”

Section: Viiib Crswnp: Comorbid Asthmamentioning

confidence: 99%

“…69,75,1347 Patients with CRSwNP tend to have better baseline QoL relative to patients with CRSsNP; however, specific symptoms such as nasal airway obstruction and olfactory disturbance tend to dominate CRSwNP. 75,77,868,1347,1348 Interestingly, patients with CRSwNP have the greatest improvement in QoL following ESS despite their relatively better baseline QoL. 75,77 …”

Section: Ess Outcomes Differences Between Crswnp and Crssnpmentioning

confidence: 99%

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International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Orlandi

Kingdom

Hwang

et al. 2016

Int Forum Allergy Rhinol

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554

888

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Background:The body of knowledge regarding rhinosinusitis (RS) continues to expand, with rapid growth in number of publications, yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS). Methods:Evidence-based reviews with recommendations (EBRRs) were developed for scores of topics, using previously reported methodology. Where existing evidence was insufficient for an EBRR, an evidence-based review (EBR) was produced. The sections were then synthesized and the entire manuscript was then reviewed by all authors for consensus. Results:The resulting ICAR:RS document addresses multiple topics in RS, including acute RS (ARS), chronic RS (CRS) with and without nasal polyps (CRSwNP and CRSsNP), recurrent acute RS (RARS), acute exacerbation of CRS (AE-CRS), and pediatric RS. Conclusion:As a critical review of the RS literature, ICAR:RS provides a thorough review of pathophysiology and evidence-based recommendations for medical and surgical treatment. It also demonstrates the significant gaps in our understanding of the pathophysiology and optimal management of RS. Too o en the foundation upon which these recommendations are based is comprised of lowerlevel evidence. It is our hope that this summary of the evidence in RS will point out where additional research efforts may be directed. C 2016 ARS-AAOA, LLC. Key Words:rhinosinusitis; chronic rhinosinusitis; acute rhinosinusitis; recurrent acute rhinosinusitis; evidence-based medicine; systematic review; endoscopic sinus surgery List of Abbreviations Used

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Section: Viiib Crswnp: Comorbid Asthmamentioning

confidence: 99%

Section: Ess Outcomes Differences Between Crswnp and Crssnpmentioning

confidence: 99%

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Orlandi

Kingdom

Hwang

et al. 2016

Int Forum Allergy Rhinol

Self Cite

554

888

View full text Add to dashboard Cite

show abstract

“…Ample evidence in the literature supports ESS, because overall quality of life is better, endoscopic scores are improved, and patients' symptoms are better controlled. 24,27,[33][34][35] An improvement in sinonasal symptoms, such as thick nasal discharge and nasal obstruction, can reasonably be achieved with appropriate surgery and postoperative care. 35 However, the return of olfaction is difficult to predict.…”

Section: Impact Of Endoscopic Sinus Surgery On Olfaction In Chronic Rmentioning

confidence: 99%

Olfaction in Endoscopic Sinus and Skull Base Surgery

Thompson

Kern

Conley

2015

Otolaryngologic Clinics of North America

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“…4–6 Longitudinal SNOT-22 data has similarly been reported across a variety of disease processes (e.g., CRS, anterior skull base neoplasms, cystic fibrosis associated sinusitis); 7–11 however, the majority of these studies are retrospective in nature and derived from a single-institution experience. One notable exception is the English and Welsh cohort, which has investigated five year follow-up SNOT-22 scores undergoing ESS with and without nasal polyposis.…”

Section: Introductionmentioning

confidence: 99%

Longitudinal improvement and stability of the SNOT‐22 survey in the evaluation of surgical management for chronic rhinosinusitis

DeConde

Mace

Alt

et al. 2014

Int Forum Allergy Rhinol

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Background Patients with chronic rhinosinustis (CRS) have significant quality-of-life (QOL) improvements following endoscopic sinus surgery (ESS). These improvements remain stable and persist between 6-months and 20-months as measured by the Rhinosinusitis Disability Index and the Chronic Sinusitis Survey. There has yet to be an evaluation of the longitudinal stability of the Sinonasal Outcome Test-22 (SNOT-22) after ESS in patients with CRS. Methods Adults with medically recalcitrant CRS who were considered surgical candidates were enrolled in a prospective, multi-center, observational cohort study from February 2011 to February 2013. Baseline evaluation of subjects included assessment of clinical characteristics, measures of CRS-specific disease severity, and QOL evaluation using the SNOT-22. Subjects were then re-evaluated at approximately 6-month, 12-month, and 18-month intervals postoperatively. Data was analyzed using repeated measures ANOVA with Bonferroni corrections for matched pairwise comparisons. Results 110 patients completed baseline evaluations and follow-up for all three postoperative time points. Significant improvement in SNOT-22 scores was seen between baseline and 6-months across both SNOT-22 total and subdomain scores (p<0.001). There was no statistically significant difference between the 6-month, 12-month, and 18-month time points in the total SNOT-22 score or its domains (p≥0.125) for both the entire cohort or subgroups (p≥0.077). Conclusions Postoperative improvement in CRS-specific QOL and symptom severity, as measured by the SNOT-22, suggest stability and durability between 6-months and 18-months. Further study on the longitudinal stability of the SNOT-22 past the 18-month timeframe will help further refine clinical study of CRS and provide further understanding of temporal improvements following ESS.

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Quality of life improvement from sinus surgery in chronic rhinosinusitis patients with asthma and nasal polyps

Abstract: CRS patients with both asthma and nasal polyps or asthma alone experience a larger QOL benefit from FESS immediately after FESS compared to CRS patients without asthma or polyps.

Cited by 45 publications

References 25 publications

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Olfaction in Endoscopic Sinus and Skull Base Surgery

Longitudinal improvement and stability of the SNOT‐22 survey in the evaluation of surgical management for chronic rhinosinusitis

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