Possible hypoglycemic effect of Aloe vera L. high molecular weight fractions on type 2 diabetic patients

Yagi, Akira; Hegazy, Sahar K; Kabbash, Amal; Wahab, Engy Abd-El

doi:10.1016/j.jsps.2009.08.007

Cited by 83 publications

(60 citation statements)

References 26 publications

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“…A previous study also found that aloesin from aloe might induce adiponectin revelation in adipocytes and thus, might control blood glucose and lipids [22]. Recently, it was reported that aloe itself and/or a certain complex molecule from aloe possesses a significant function in controlling blood glucose and lipids [23,24].…”

Section: Discussionmentioning

confidence: 94%

A study on verifying the effectiveness of 4-week composite weight-loss dietary supplement ingestion on body composition and blood lipid changes in middle-aged women

Chun¹,

Lee²,

Park³

et al. 2015

J. Exerc. Nutr, Biochem.

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study on verifying the effectiveness of 4-week composite weight-loss dietary supplement ingestion on body composition and blood lipid changes in middle-aged women. JENB., Vol. 19, No. 3, pp.211-216, 2015 [Purpose] The purpose of this study was to investigate the effectiveness of a composite weight-loss dietary supplement on body composition and blood lipid changes in middle-aged women.[Methods] Thirty seven middle-aged women living in the Kyunggi area participated in this study and they were randomly divided into 2 groups (Dietary supplement ingestion group; DG, n = 20 and Placebo group; PG, n = 17). Blood draw and dual energy x-ray (DEXA) measurements were conducted to examine changes in body composition and blood lipids.[Results] There were no significant changes in weight and BMI in both groups. There was an interaction between the composite weight-loss dietary supplement intake and lean body mass in DG and there was a significant decrease in percent body fat in DG. Blood lipid changes in the study results showed that there was no significant difference in TC, TG, and LDL in both groups; however, there was a significant interaction between the composite weight-loss dietary supplement intake and HDL-C as well as an increase in the HDL-C of DG.[Conclusion] In conclusion, it seems that 4-week ingestion of the composite weight-loss dietary supplement decreased body fat, increased lean body mass, and increased HDL-C. Therefore, the composite weight-loss dietary supplement is expected to prevent obesity and induce health improvements in middle-aged women.

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Section: Discussionmentioning

confidence: 94%

A study on verifying the effectiveness of 4-week composite weight-loss dietary supplement ingestion on body composition and blood lipid changes in middle-aged women

Chun¹,

Lee²,

Park³

et al. 2015

J. Exerc. Nutr, Biochem.

View full text Add to dashboard Cite

show abstract

“…In addition, the thermodynamic functions enthalpy and entropy for the reaction were also carried out [27] . Patented hyper-dry system in combination of freeze-dry technique with micro wave and far infrared radiation was used for the preparation of Aloe vera high molecular weight fractions (AHM) which contain barbaloin as phytoconstituents [28] . A reversedphase HPLC method was developed for the quantitative analysis of barbaloin in Aloe ferox Miller and aloe-related products using C18 column with a water-methanol gradient and UV detection at 297 nm [29] .…”

Section: Analytical Methods Of Barbaloinmentioning

confidence: 99%

Barbaloin: A concise report of its pharmacological and analytical aspects

Patel

Tahilyani³

2012

Asian Pacific Journal of Tropical Biomedicine

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“…This study showed that Aloe vera high molecular weight fractions exhibited a significant hypoglycaemic effect. It can lower not only the glucose level but also the triglycerides level which are often high in diabetic patients [48].…”

Section: Radiation-and Chemotherapy-induced Disordersmentioning

confidence: 99%

Evaluation of clinical effectiveness of Aloe vera – a review

Zagórska‐Dziok¹,

Furman‐Toczek²,

Dudra-Jastrzębska³

et al. 2017

J Pre Clin Clin Res.

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Naturally occurring products have gained popularity in recent decades, especially due to their less adverse effects on human health. Various Aloe species are widespread all over the world. Aloe vera is one of the plants exhibiting multiple benefits and has gained considerable importance in clinical research. Historically, it has been used for a variety of medicinal purposes. It has attracted the attention of many researchers because of its different properties. More than 200 different biologically active substances were found in this plant that contributed to the fact it has been used to treat various types of diseases. The healthy effect of Aloe vera is primarily attributed to the polysaccharides contained in the gel of the leaves. It has been traditionally used to treat various conditions, including psoriasis, sunburn or radiation-related dermatitis, mucositis, oesophagitis or lichen planus. Aloe vera has also found application in wound healing, treatment of burns, protection against skin damage caused by X-ray, intestinal problems, reduction of plaque and gingivitis, regulating the levels of plasma lipoproteins, reduction of blood sugar levels and improving the immune system. Other biological activities of aloe, such as antifungal, antibacterial, antiviral, anti-inflammatory, anticancer and immunomodulatory have also been documented in numerous studies. This review examines the possible applications of Aloe vera in clinical trials.

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Possible hypoglycemic effect of Aloe vera L. high molecular weight fractions on type 2 diabetic patients

Cited by 83 publications

References 26 publications

A study on verifying the effectiveness of 4-week composite weight-loss dietary supplement ingestion on body composition and blood lipid changes in middle-aged women

A study on verifying the effectiveness of 4-week composite weight-loss dietary supplement ingestion on body composition and blood lipid changes in middle-aged women

Barbaloin: A concise report of its pharmacological and analytical aspects

Evaluation of clinical effectiveness of Aloe vera – a review

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