Positive pressure therapy induced harm – non-linear, adaptive and maladaptive responses

Thomas, Robert J.

doi:10.1016/j.sleep.2015.07.008

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Cited by 3 publications

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“…With an analogy to auditory noise cancellation, the device is cancelling the variations in tidal volume but the driving "noise," the high loop gain-based periodic breathing, continues unabated. Moreover, adaptive ventilation can cause substantial patientventilatory desynchrony, 17 which remains unidentified. In the SERVE-HF trial, up to a device detected AHI TIDAL 10 events/h of use was taken as a success, which likely overlooked a large degree of ongoing unrecognized periodic breathing, in addition to the basic scoring issues already mentioned.…”

Section: Esti M Ati O N Ch a Lleng Es Dur I Ng A Da Pti V E V Enti L mentioning

confidence: 99%