Portal vein thrombosis despite anticoagulation in a person with diabetes

A Rare Twist of the Forgotten Disease: A Case of Fusobacterium necrophorum Sepsis with Portomesenteric Thrombosis and a Review of the Literature

“…septicemia [4]. We hereby report a case of septic portomesenteric thrombosis secondary to Fusobacterium necrophorum bacteremia in the setting of sigmoid colitis to add to a total of 21 cases of Fusobacterium-spp.-infection-related pylephlebitis reported in the literature [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27].…”

Protein C Gene Mutation in an Older Adult Patient with Clostridium perfringens Septicemia-Related Visceral Vein Thrombosis

“…Several conditions known to cause VVT, 4,5 including hepatic cirrhosis, pancreatitis, and malignancies, were ruled out in our case; however, the patient had Clostridium sepsis, and diabetes mellitus. 6 We first thought that his VVT was due to a pathological condition similar to thrombophlebitis of the portal vein, caused by C. perfringens septicemia 7 ; however, we discovered that probably inherent protein C deficiency was also involved in the development of VVT.…”

“…He was suspected to have cholecystitis, based on the abdominal CT image after admission and following laboratory data: white blood cells, 14,900/µL; hemoglobin, 14. 6 4.79 (0.3-1.3) mg/dL; hyaluronic acid, 287 (<50) ng/mL, and type 4 collagen, 339 (<140) ng/mL, but with normal total protein and albumin/globin ratio. Renal and cardiac functions were slightly abnormal with serum blood urea nitrogen, 20.9 mg/dL and creatinine, 2.06 (0.64-1.11) mg/dL, and troponin I was slightly elevated with 0.151 (<0.03) ng/mL.…”