2021
DOI: 10.1155/2021/6699867
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A Rare Twist of the Forgotten Disease: A Case of Fusobacterium necrophorum Sepsis with Portomesenteric Thrombosis and a Review of the Literature

Abstract: Abdominal variants of Lemierre’s syndrome presenting with pylephlebitis are rare, and the role of anticoagulation in treatment is controversial. We hereby report a case of pylephlebitis secondary to F. necrophorum bacteremia in a 57-year-old female originating from bacterial translocation secondary to colitis, who developed a favorable outcome with prompt treatment with antibiotics and anticoagulation. We also perform a literature review on similar cases in the literature and discuss management options of this… Show more

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Cited by 7 publications
(17 citation statements)
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“…Lemierre's syndrome is a specific form of septic thrombophlebitis, which includes venous thrombosis associated with local bacterial infection occurring at several anatomic locations [ 11 ]. Current literature describes a variant of Lemierre's syndrome involving an older demographic who present with an initial infection and thrombosis of the portal vein [ 8 , 12 ]. The pathogenesis of the thrombus formation remains the same; however, the strain of Fusobacterium involved in the portal vein thrombosis differs from that of a typical case of Lemierre's syndrome.…”
Section: Discussionmentioning
confidence: 99%
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“…Lemierre's syndrome is a specific form of septic thrombophlebitis, which includes venous thrombosis associated with local bacterial infection occurring at several anatomic locations [ 11 ]. Current literature describes a variant of Lemierre's syndrome involving an older demographic who present with an initial infection and thrombosis of the portal vein [ 8 , 12 ]. The pathogenesis of the thrombus formation remains the same; however, the strain of Fusobacterium involved in the portal vein thrombosis differs from that of a typical case of Lemierre's syndrome.…”
Section: Discussionmentioning
confidence: 99%
“…Typically, Fusobacterium necrophorum is involved, but in the atypical cases, the responsible pathogen points to Fusobacterium nucleatum [ 12 ]. In light of the recent report by Lazar et al, describing several cases of portomesenteric thrombosis due to Fusobacterium necrophorum infection [ 8 ], atypical Lemierre's syndrome may be attributed to Fusobacterium spp. infection.…”
Section: Discussionmentioning
confidence: 99%
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