POMES: An Open-source Software Tool to Generate Porous/Roughness on Surfaces

Dinis, Jairson C.; Moraes, Thiago; Amorim, Paulo; Moreno, Mario R.; Nunes, Amanda Amorin; Silva, Jorge Vicente Lopes da

doi:10.1016/j.procir.2015.07.085

Cited by 5 publications

(4 citation statements)

References 14 publications

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“…CPs are involved in the inducement of cell proliferation that is related to the enhancement of cell adhesion. 29 Chitosan with the various CP mixtures performed strongly in terms of enhancing cell adhesion and proliferation. 30 CP has the ability to enhance biomarkers for ALP activity and calcium content.…”

Section: Discussionmentioning

confidence: 93%

The bone-mimicking effect of calcium phosphate on composite chitosan scaffolds in maxillofacial bone tissue engineering

Sangkert

Kamolmatyakul

Meesane

2020

Journal of Applied Biomaterials & Functional Materials

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Section: Discussionmentioning

confidence: 93%

The bone-mimicking effect of calcium phosphate on composite chitosan scaffolds in maxillofacial bone tissue engineering

Sangkert

Kamolmatyakul

Meesane

2020

Journal of Applied Biomaterials & Functional Materials

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“…In addition to nanoindentation studies, we also measured the surface roughness of the biomineralized composite. It was shown that increased roughness aids in forming an interface between the scaffold and native bone tissue [ 98 ]. Additionally, surface roughness allows for the adhesion as well as proliferation of osteoblasts and increased collagen synthesis [ 99 , 100 ].…”

Section: Resultsmentioning

confidence: 99%

Biomineralization of Fucoidan-Peptide Blends and Their Potential Applications in Bone Tissue Regeneration

Pajovich

Banerjee

2017

JFB

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Fucoidan (Fuc), a natural polysaccharide derived from brown seaweed algae, and gelatin (Gel) were conjugated to form a template for preparation of biomimetic scaffolds for potential applications in bone tissue regeneration. To the Fuc–Gel we then incorporated the peptide sequence MTNYDEAAMAIASLN (MTN) derived from the E-F hand domain, known for its calcium binding properties. To mimic the components of the extracellular matrix of bone tissue, the Fuc–Gel–MTN assemblies were incubated in simulated body fluid (SBF) to induce biomineralization, resulting in the formation of β-tricalcium phosphate, and hydroxyapatite (HAp). The formed Fuc–Gel–MTN–beta–TCP/HAP scaffolds were found to display an average Young’s Modulus value of 0.32 GPa (n = 5) with an average surface roughness of 91 nm. Rheological studies show that the biomineralized scaffold exhibited higher storage and loss modulus compared to the composites formed before biomineralization. Thermal phase changes were studied through DSC and TGA analysis. XRD and EDS analyses indicated a biphasic mixture of β-tricalcium phosphate and hydroxyapatite and the composition of the scaffold. The scaffold promoted cell proliferation, differentiation and displayed actin stress fibers indicating the formation of cell-scaffold matrices in the presence of MT3C3-E1 mouse preosteoblasts. Osteogenesis and mineralization were found to increase with Fuc–Gel–MTN–beta–TCP/HAP scaffolds. Thus, we have developed a novel scaffold for possible applications in bone tissue engineering.

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“…The first researcher working on TMPS structures is Schwarz[ 101 ], followed by Schoen[ 102 ] and Karcher[ 103 ]. An open-source software based on the generation of the TPMS structures around any surface was developed, which is known as POMES (Porous and Modifications for Engineering Surfaces)[ 104 ]. It allows generation of different porous and roughness morphology on surfaces using such structures as Scwartz P, Scwartz D, Gyroid, Neovius and others.…”

Section: Software For Bioprintingmentioning

confidence: 99%

Software for Bioprinting

Pakhomova¹,

Popov²,

Maltsev³

et al. 2024

IJB

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The bioprinting of heterogeneous organs is a crucial issue. To reach the complexity of such organs, there is a need for highly specialized software that will meet all requirements such as accuracy, complexity, and others. The primary objective of this review is to consider various software tools that are used in bioprinting and to reveal their capabilities. The sub-objective was to consider different approaches for the model creation using these software tools. Related articles on this topic were analyzed. Software tools are classified based on control tools, general computer-aided design (CAD) tools, tools to convert medical data to CAD formats, and a few highly specialized research-project tools. Different geometry representations are considered, and their advantages and disadvantages are considered applicable to heterogeneous volume modeling and bioprinting. The primary factor for the analysis is suitability of the software for heterogeneous volume modeling and bioprinting or multimaterial three-dimensional printing due to the commonality of these technologies. A shortage of specialized suitable software tools is revealed. There is a need to develop a new application area such as computer science for bioprinting which can contribute significantly in future research work.

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POMES: An Open-source Software Tool to Generate Porous/Roughness on Surfaces

Cited by 5 publications

References 14 publications

The bone-mimicking effect of calcium phosphate on composite chitosan scaffolds in maxillofacial bone tissue engineering

The bone-mimicking effect of calcium phosphate on composite chitosan scaffolds in maxillofacial bone tissue engineering

Biomineralization of Fucoidan-Peptide Blends and Their Potential Applications in Bone Tissue Regeneration

Software for Bioprinting

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