Polyploidy in Human Leucocyte Cultures treated with Cysteamine and Irradiation

Jackson, J. F.; Hill, Frank

doi:10.1038/2141155a0

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Altered Sulphur Metabolism Associated With Cellular Processes1

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1970

1989

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Cited by 10 publications

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“…Thus, the multinucleated giant cells produced in cell cultures containing supraoptimal concentrations of sulphane sulphur sources (Fig. 2; [152,153]) are very similar to the giant cells induced by many viruses in vitro and in vivo [154]. The mechanism by which viruses cause formation of giant cells is not known [154] but the findings reviewed here suggest that it may involve accelerated production of sulphane sulphur induced by the virus, possibly as a mechanism for inactivating a specific set of host cell enzymes.…”

Section: Altered Sulphur Metabolism Associated With Cellular Processesmentioning

confidence: 53%

Sulphane sulphur in biological systems: a possible regulatory role

Toohey¹

1989

Biochemical Journal

228

186

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cess appears to be essential for making the sulphur cyanolysable as evidenced by the acquisition of cyanolysability when ,-mercaptopyruvate is converted to the disulphide; only the latter can give the -S(S)form. This tautomerization can also occur in polysulphides and the lability of the sulphur in polysulphides with n > 3 compared with the stability of dialkyldisulphides (n = 2) again reflects the capacity to tautomerize

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