“…Nowadays, this crop is widely distributed all over the world, even though it is mainly concentrated in the Mediterranean regions, where it contributes to the agricultural economy (Pandino, Lombardo, & Mauromicale, 2013). In recent years, an increasing demand for functional foods with added value has led to a renewed interest for this crop (Lombardo, Pandino, Mauro, & Mauromicale, 2009;Pandino, Lombardo, & Mauromicale, 2011;Pandino, Lombardo, Mauromicale, & Williamson, 2012a;Pandino, Lombardo, Williamson, & Mauromicale, 2012b). In this sense, globe artichoke has shown to possess 'in vitro' hepatoprotective, anticarcinogenic, antioxidative, antibacterial, anti-HIV, bile-expelling, and diuretic properties as well as the ability to inhibit cholesterol biosynthesis and low density lipoprotein (LDL) oxidation (Lattanzio, Kroon, Linsalata, & Cardinali, 2009).…”