2022
DOI: 10.1371/journal.pone.0268984
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Polymorphisms of adiponectin gene and gene–lipid interaction with hypertension risk in Chinese coal miners: A matched case-control study

Abstract: Objective Low serum adiponectin level can predict hypertension development, and adiponectin gene (ADIPOQ) polymorphisms have been reported to be linked with hypertension risk. Whereas, the interaction between ADIPOQ polymorphisms and environmental factors on the susceptibility of hypertension remained unclear. The purpose of this study was to explore the relationship of ADIPOQ polymorphisms with hypertension risk and their interaction with lipid levels in coal miners. Methods A matched case-control study wit… Show more

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Cited by 2 publications
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“…(3) Renal microcirculation dysfunction caused by hyperlipidemia may also be involved in the development of hypertension 29 . (4) Genetic factors, such as Apolipoprotein (apo) A-I, Apolipoprotein e, microsomal TG transporter and lipoprotein lipase genes may be important genetic factors for hyperlipidemia and hypertension 30 .…”
Section: Discussionmentioning
confidence: 99%
“…(3) Renal microcirculation dysfunction caused by hyperlipidemia may also be involved in the development of hypertension 29 . (4) Genetic factors, such as Apolipoprotein (apo) A-I, Apolipoprotein e, microsomal TG transporter and lipoprotein lipase genes may be important genetic factors for hyperlipidemia and hypertension 30 .…”
Section: Discussionmentioning
confidence: 99%