2007
DOI: 10.1590/s1415-47572007000400009
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Abstract: The exon 2-3 region of bovine major histocompatibility complex (MHC) class I BoLa-A gene was investigated for polymorphisms in three breeds of cattle originated in the Indian subcontinent namely Sahiwal, Tharparkar, Hariana, as well as crossbred (Bos taurus x Bos indicus) cattle and Jersey, the exotic breed (Bos taurus). The PCR amplified fragment of 714 bp showed distinct DdeI-, TaqI-and HinfI-RFLP patterns, thus confirming a higher degree of polymorphism in this region. To our knowledge this is the first rep… Show more

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Cited by 4 publications
(1 citation statement)
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“…Among identified immune-related genes, the bovine lymphocyte antigen (BoLA) caught the attention of the researcher, as it was directly involved in antigen presentation. The BoLA gene located on chromosomes BTA 23 [30], and generally known as the MHC of cattle, was reported to play an integral role in immune responsiveness and susceptibility to the diseases of the host animal [31]. MHC is a cell surface glycoprotein molecule, having the binding ability to foreign peptides, such as viral proteins, and provides context for the recognition of T-lymphocytes responsible for cell-mediated immunity [32,33].…”
Section: Discussionmentioning
confidence: 99%
“…Among identified immune-related genes, the bovine lymphocyte antigen (BoLA) caught the attention of the researcher, as it was directly involved in antigen presentation. The BoLA gene located on chromosomes BTA 23 [30], and generally known as the MHC of cattle, was reported to play an integral role in immune responsiveness and susceptibility to the diseases of the host animal [31]. MHC is a cell surface glycoprotein molecule, having the binding ability to foreign peptides, such as viral proteins, and provides context for the recognition of T-lymphocytes responsible for cell-mediated immunity [32,33].…”
Section: Discussionmentioning
confidence: 99%