Polymorphism of ESR, FSHß, RBP4, PRL, OPN genes and their influence on morphometric traits of gilt reproductive tract before sexual maturity

Abstract

The aim of the study was to examine the effect of gene polymorphism on the development of the reproductive system in 100 Polish Large White and 100 Polish Landrace gilts. Gilts were slaughtered when they reached 100 kg, and their uterus weight and length, as well as the ovary weight and volume were evaluated. Differences between gilts of both breeds were observed in some traits of the reproductive system, such as the uterine weight without the broad ligament (P ≤ 0.05) and the uterine capacity (P ≤ 0.01). Polish Landrace gilts were characterized with higher uterine weight and higher uterine capacity; they were also younger at the time of slaughter (P ≤ 0.05). No BB homozygote relative to the oestrogen receptor gene was found in the examined populations of Polish Landrace gilts. Also, a very low number of gilts with the AA genotype relative to follicle stimulating hormone gene was observed in both populations. Polymorphism of the examined genes had an effect on numerous traits which define the size of particular uterine sections, and thus it influenced the development of potential fertility of gilts before they entered the reproductive cycle. Based on our results we can conclude that genetic determination of reproductive potential occurs already in prepubertal gilts. The results may be used for the prognosis of fertility potential in gilts.

Association of RBP4 Genotype with Phenotypic Reproductive Traits of Sows

“…Similar allelic frequencies have been reported for Large White and Landrace × Large White populations [ 1 , 7 , 12 – 14 ] and in Black Slavonian sows [ 15 ]. Higher allelic values for A allele have been previously reported in Duroc [ 16 ] and in Polish Landrace [ 17 ] sows populations, while lower values have been reported by Kapelański et al [ 18 ] in Polish Landrace and in Police Large White populations. The analyzed population was found to deviate from the Hardy-Weinberg equilibrium due to the higher value of heterozygous genotype, as also reported by Omelka et al [ 19 ].…”

Effect of ESR, FSHB and PRLR Genes on Sperm Traits of Landrace and Yorkshire Boars in the Tropical Environmental Conditions of Vietnam

“…The association between Estrogen Receptor (ESR), Follicle Stimulating Hormone Beta (FSHB) and Prolactin Receptor (PRLR) polymorphisms and reproductive traits in gilts and sows was reported in previous studies (Rothschild et al 1996;van Rens et al 2002;Korwin-Kossakowska et al 2003;Kapelański et al 2013;Hunyadi-Bagi et al 2016;Vega et al 2018;Melnikova et al 2019). For ESR, the presence Effect of ESR, FSHB and PRLR Genes on Sperm Traits of Landrace and Yorkshire Boars in the Tropical Environmental... of allele B was significantly associated with an increased litter size (Rothschild et al 1996;Short et al 1997;Melnikova et al 2019).…”

“…Similarly, Korwin-Kossakowska et al (2003) reported allele A frequencies of more than 0.90 in a synthetic pig line, which was selected for reproductive traits. In contrast, studies of Kapelański et al (2013) and Polasik et al (2016) showed that BB genotype in Landrace gilts was predominant. In the last two study, the frequency of BB was more than 0.82.…”

Association of non-synonymous SNPs of <i>OPN</i> gene with litter size traits in pigs

“…The SINE polymorphisms at intron 6 of the porcine OPN gene were found to be associated with litter size as well as body weight at birth and weaning traits Niu et al, 2008;Zhang et al, 2010). These SINE polymorphisms were found to be associated with the uterine weight in Polish Landrace pigs (Kapelanski et al, 2013). Moreover, two synonymous SNP (c.559A>C and c.574C>G) of the porcine OPN gene were associated with their expres- sion levels in uterine tissues (Korwin-Kossakowska et al, 2013).…”