Polymers in the Treatment of Wounds: Realities and Perspectives

Legonkova, O.A.; Belova, M. S.; Асанова, Л.Ю.; Алиев, А. Д.; Чалых, А. Е.

doi:10.17650/2408-9613-2016-3-1-12-18

Cited by 4 publications

(4 citation statements)

References 14 publications

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“…The standard technology is pouring on a surface. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] Preparing gelling solution, the first stage of which is the dissolution stage precedes pouring. Depending on the properties of the ingredients, it is possible to dissolve hydrophilic polymers in water separately, heating it, and to dissolve active and auxiliary substances in matching solvents with further combining the formed solutions; or to dissolve auxiliary substances insolvent or a mixture of solvents, and then adding active pharmaceutical ingredients to this solution.…”

Section: Technological Processmentioning

confidence: 99%

“…A kind of a dosage form for treating patients with skin defects, which are the results of purulent infection of soft tissues, are wound dressings. [2,7,12,13,36] The correct choice of a wound dressing with a certain mechanism of action can significantly improve the effectiveness of the purulent wounds treatment. Nowadays, more than 300 types of wound dressings are used in clinical practice.…”

Section: Application Of Films In Medicinementioning

confidence: 99%

“…[1] Developing new medications with active pharmaceutical ingredients immobilized on polymer carriers -films -which are used in various fields of medicine -is becoming more and more popular. [1][2][3][4] Films are solid or soft preparations of a suitable size and shape consisting of a matrix in which the active ingredient is incorporated or an active substance surrounded by a membrane controlling the release rate. Medicated films are the application dosage forms and intended to introduce active substances into the body through the skin, periodontal tissue, or mucous membranes.…”

Section: Introductionmentioning

confidence: 99%

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Хохленкова

2017

AJP

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Introduction: Nowadays, biopolymers and biomaterials are an actively developing field, interesting both for specialists from various fields of science and for society at large. The range of polymers of both natural and synthetic origin is constantly expanding, but only a few of them are used in pharmaceutical production and medical practice. Due to the composition of polymers and active pharmaceutical ingredient, films are a promising form for applying in dentistry, ophthalmology, surgery, and other fields of medicine. Materials and Methods: In the work marketing and economic research methods are used to ground social and medical practicability of developing new dental products for local treatment. Results and Discussions: Based on the data of modern scientific literature, the requirements for medicinal films are outlined, their classification is given. Approaches to the choice of active and auxiliary substances in the process of developing new film formulations are described. The prospects of using films in surgery, dentistry, ophthalmology, and dermatology are shown. Conclusions: Based on the review, polymer films have been classified, and the requirements for the given dosage form have been defined. Approaches to selecting active and auxiliary ingredients have been considered. The main aspects of the technological process for the preparation of films are described. The ways of rational application of films in medical practice have been highlighted.

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Section: Technological Processmentioning

confidence: 99%

Section: Application Of Films In Medicinementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Untitled

Хохленкова

2017

AJP

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“…By the term “performance characteristics of medical products” we understand a set of properties that reveal a possibility of applying this medical product and using it effectively [ 14 ]. For the purpose of a more comprehensive analysis we divided the performance properties into the following groups (according to the methods of identification): chemical, physical, organoleptic (see the Table ).…”

Section: Introductionmentioning

confidence: 99%

In vitro Evaluation of Performance Properties of Sponge Hemostatic Dressings (Review)

Северинов¹,

Lazarenko²,

Sotnikov³

et al. 2020

Sovrem Tehnol Med

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Dressings for restoring organ defects and/or hemostasis in the injury site are being actively applied in operational units. These dressings are used in various surgeries and are widely represented in the foreign and domestic markets of medical products. Many local implants have different levels of hemostatic activity, which requires standardization of the algorithm of choice and the methods of their study. Here the methods of studying the performance properties of hemostatic implants in vitro have been considered and evaluation criteria of their physical, chemical and organoleptic properties in vitro have been proposed. This will allow a researcher to choose optimal variants of samples for further experiments on biological models more effectively as well as to save funds, time and reduce the number of experiments in vivo.

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