Polymeric biomaterial hydrogels. I. Behavior of some ionotropic cross-linked metal-alginate hydrogels especially copper-alginate membranes in some organic solvents and buffer solutions

Abstract

The change in rheological and mechanical properties for some ionotropic cross-linked metal-alginate hydrogel complexes in particularly copper-alginate membranes in the presence of some organic solvents (benzene, toluene, xylene, carbon tetrachloride, ace-tone, chloroform, dichloroethane, isobutyl alcohol and ethyl alcohol) or buffer solutions (acetates, borates and universal buffers) have been investigated. The experimental results showed a remarkable tendency of the studied hydrogels for shrinking in polar solvents, whereas no influence was observed for the hydrogels in non-polar solvents. On the other hand, the gels were found to swell or shrink in the buffer solutions depending on the pH of the buffer used. The swelling extent for hydrogel spheres was found to decrease in the order Cu > Ba ≈ Ca > Zn > Pb-alginates in universal buffers of pH = 5.33. The factors affected this behavior have been examined and discussed

Biosorption Performance of Encapsulated Candida krusei for the removal of Copper(II)

“…This is in agreement with the research work in Hassan et al . 41 which focused on the ionotropic cross-linking of metal alginate. They showed that the cross-linking of alginates with divalent metal ions at a stoichiometric ratio of 2:1 which correlates with this result of the pseudo-second-order kinetics fitting.…”

Alginate-Based Hydrogel Containing Taurine-Loaded Chitosan Nanoparticles in Biomedical Application

“…However, rich carboxylic acid (-COOH) and hydroxyl (-OH) groups on this polymer limit cell adhesion (19,20). Chitosan grafting is a common way to enhance hydrophobicity (19,20). In this study, the existence of nanoparticles clearly decreased the contact angle from 97 ± 3°in alginate hydrogel to 61 ± 4°in alginate/chitosan nanoparticle hydrogel.…”

“…Among natural polymers, alginate has been extensively used in biomedical application because of its superior degradation ability and nontoxicity of its product. However, rich carboxylic acid (-COOH) and hydroxyl (-OH) groups on this polymer limit cell adhesion (19,20). Chitosan grafting is a common way to enhance hydrophobicity (19,20).…”

“…The swelling ratio can be used as a simple method to characterize stability and water uptake of hydrogels. Permeation of nutrients or air and also cellular metabolic products into hydrogels and out of hydrogels, respectively will be evaluated with the degree of swelling (19)(20)(21). The ratio of swelling hydrogels in a time-dependent response is shown in Figure 3A.…”

“…Degradation of hydrogel is recognized as another crucial specification that manages the stability of the scaffold under physiological conditions (10,20,21). As blood serum is composed of different inorganic ions such as sodium, potassium, calcium, and magnesium, as well as organic compounds such as uric acid and amino acids, the evaluation of in vitro degradation of fabricated scaffold in a media containing different salts has a significant role in its biomedical application.…”