Polymer biquinolyl-containing complexes of Pd(ii) as efficient catalysts for cyanation of aryl and vinyl halides with K₄Fe(CN)₆

Abstract

Stereo- and chemoselective cyanation of compounds containing Csp2–Br bonds catalyzed by Pd–polymer complexes is reported.

Recent advances and prospects in the palladium-catalyzed cyanation of aryl halides

“…A polymer based catalyst having palladium( ii ) ions coordinated to biquinolyl fragments in the polyamic type polymer chain was introduced by Magdesieva et al in 2016. 53 The source of cyanide was K 4 [Fe(CN) 6 ] (Scheme 19). Here, the catalyst was capable of bringing about the cyanation of aryl halides in good yields.…”

An overview of microwave assisted cyanation reactions

“…Polymer biquinolyl bearing complexes of Pd (II) were efficiently used as catalysts for cyanation reaction of aryl and vinyl halides. [63] Iodobenzene was the model substrate chosen for cyanation of aryl halides and the reaction was carried out using nontoxic K 4 Fe(CN) 6 in the presence of Na 2 CO 3 in NMP a microwave absorbing polar solvent (Scheme 30). The same reaction conditions were applied for the cyanation of vinyl halides.…”

Pd‐Polypyrrole Nanocomposite in Environmentally Friendly Synthesis of Vinylnitriles Using K4Fe(CN)6

“…It describes application of the Pd/PPy composite for cyanation of vinyl derivatives. Transition metal catalyzed cyanation of vinyl halides with K 4 Fe(CN) 6 is much less investigated than that of their aryl counterparts. Few publications available are mainly restricted to the synthesis of substituted cinnamonitriles .…”