Polyester functional graphenic materials as a mechanically enhanced scaffold for tissue regeneration

Schmidt, S.; Holt, Brian D.; Arnold, Anne M.; Sydlik, Stefanie A.

doi:10.1039/c9ra10646d

Cited by 9 publications

(10 citation statements)

References 44 publications

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“…Syntheses of GO and CG were conducted as previously reported . As expected, X-ray photoelectron spectroscopy (XPS) survey scans indicate that GO contained a variety of oxygen functional groups with a C/O ratio of 3:1, while CG contained a reduced carbon sheet but with a higher fraction of carboxylic acids, with a C/O ratio of 4:1.…”

Section: Resultsmentioning

confidence: 65%

Regeneratable Graphene-Based Water Filters for Heavy Metal Removal at Home

2023

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At-home water filters for drinking water are used by over 100 million Americans. These filters are successful at removing heavy metals from drinking water; however, when heavy metals are present, filters can reach saturation quickly. This currently requires a full filter replacement; treating and regenerating (re-activating) the filter are not currently recommended by filter manufacturers. Here, we present a sustainable graphene-based water filter that can be regenerated by treatment with hot (80 °C) water or vinegar (mild acid). The filter has multiple desirable properties for heavy metal adsorption, including high surface area, conjugation, and oxygen-containing functional groups. This regeneratable filtration technology removes 3- to 65-fold more heavy metals (lead, cadmium, and mercury) from tap water than activated charcoal. Further, the filter can undergo a simple regeneration treatment, allowing for up to 3 cycles of reuse before metal breakthrough occurs. Due to the decreased frequency of filter replacement compared to current technologies, this graphene-based water filter could seamlessly integrate into existing at-home water filtration technologies, providing a more sustainable filter option.

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Section: Resultsmentioning

confidence: 65%

Regeneratable Graphene-Based Water Filters for Heavy Metal Removal at Home

2023

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“…Aliphatic polyesters are the most studied and widely used in the application of synthetic polymers, which can be divided into polyglycolic acid (PGA), polylactic acid (PLA), polycaprolactone (PCL) and other copolymers [ 120 , 121 ]. Among them, the PLA is the most popular.…”

Section: The Materials For Microspheresmentioning

confidence: 99%

Application of Biomedical Microspheres in Wound Healing

Yang

Zhang

Gan

et al. 2023

IJMS

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Tissue injury, one of the most common traumatic injuries in daily life, easily leads to secondary wound infections. To promote wound healing and reduce scarring, various kinds of wound dressings, such as gauze, bandages, sponges, patches, and microspheres, have been developed for wound healing. Among them, microsphere-based tissue dressings have attracted increasing attention due to the advantage of easy to fabricate, excellent physicochemical performance and superior drug release ability. In this review, we first introduced the common methods for microspheres preparation, such as emulsification-solvent method, electrospray method, microfluidic technology as well as phase separation methods. Next, we summarized the common biomaterials for the fabrication of the microspheres including natural polymers and synthetic polymers. Then, we presented the application of the various microspheres from different processing methods in wound healing and other applications. Finally, we analyzed the limitations and discussed the future development direction of microspheres in the future.

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“…[152][153][154] As for PLA, PGA, PLGA, and PCL, they are all FDA approved polyesters and have been used as implants for decades due to their favorable mechanical properties and ability to be degraded into non-toxic products in a physiological environment. [155][156][157][158] On the other hand, they can melt under heating or dissolve in an organic solvent, which makes them suitable for the preparation of MNs. Li et al 159 proved that the excellent mechanical properties of the PLA MN patch enable it to penetrate pig skin after repeated use and this patch have the potential to enhance the transdermal delivery of insulin.…”

Section: Polymersmentioning

confidence: 99%