Polycystic ovary syndrome in adolescents

Rothenberg, Stephanie S.; Beverley, R. M.; Barnard, Emily P.; Baradaran-Shoraka, Massoud; Sanfilippo, Joseph S.

doi:10.1016/j.bpobgyn.2017.08.008

Cited by 58 publications

(45 citation statements)

References 42 publications

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“…It should be considered that PCOS development risk factors include early menarche, early pubarche, low birth weight, and obesity. Also, early diagnosis of the syndrome in the pubescence period is very important due to the risk of endometrium carcinoma development, cardiovascular diseases, or diabetes type 2 in life later stages [11,[13][14][15][16][17].…”

Section: Diagnosismentioning

confidence: 99%

“…Menstruations remaining irregular for over two years after menarche is a risk factor of menstruation disturbances in later periods of life [11,14,15,17]. In the first post menarche year, bleeding more frequently than every 20 days and more rarely than every 90 days is considered abnormal and calls for diagnostics [13][14][15]20]. After the first two years of menarche, in the majority of girls, the cycles are from 20 to 45 days.…”

Section: Ovary Function Assessment In Pcosmentioning

confidence: 99%

“…After the first two years of menarche, in the majority of girls, the cycles are from 20 to 45 days. In turn, in subsequent years, irregular menstruations are those more frequent than every 20 days and rarer than every 45 days [15,20]. Primary amenorrhoea is no menstruation up to the 16 th year of life or no menstruation in the first 2-3 years of thelarche.…”

Section: Ovary Function Assessment In Pcosmentioning

confidence: 99%

“…Primary amenorrhoea is no menstruation up to the 16 th year of life or no menstruation in the first 2-3 years of thelarche. Secondary amenorrhoea can be recognised when no menstruation is observed for longer than three months [15,21].…”

Section: Ovary Function Assessment In Pcosmentioning

confidence: 99%

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Stanowisko Polskiego Towarzystwa Endokrynologicznego, Polskiego Towarzystwa Ginekologów i Położników oraz Polskiego Towarzystwa Endokrynologii Ginekologicznej w sprawie diagnostyki i leczenia zespołu policystycznych jajników

Milewicz¹,

Kudła²,

Spaczyński³

et al. 2018

Endokrynologia Polska

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Polycystic ovary syndrome (PCOS) diagnosis and therapy still arouse a lot of controversy. Each year brings new information, so, having collected the experience of three scientific societies, we present contemporary recommendations concerning PCOS diagnostics and treat-ment. In adult female diagnosis, we still use the Rotterdam criteria, which is two out of three of the follwing characteristics: a) ovulation abnormality, b) clinical or biochemical hyperandrogenism, and c) polycystic ovaries. In the case of teenagers, diagnostic criteria are as follows: menstruation disturbances two years after menarche and clinical or biochemical hyperandrogenism. The presence of polycysti-cally abnormal ovaries is not necessary. The consensus paper presents the threats resulting from imperfect diagnostic methods applied in PCOS (hyperandrogenism diagnostics, ultrasound examination of ovaries). Suggested therapy includes personalised schemes according to the dominant PCOS phenotype, i.e. metabolic, hyperandrogenic, or reproductive ones.

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Section: Diagnosismentioning

confidence: 99%

Section: Ovary Function Assessment In Pcosmentioning

confidence: 99%

Section: Ovary Function Assessment In Pcosmentioning

confidence: 99%

Section: Ovary Function Assessment In Pcosmentioning

confidence: 99%

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Stanowisko Polskiego Towarzystwa Endokrynologicznego, Polskiego Towarzystwa Ginekologów i Położników oraz Polskiego Towarzystwa Endokrynologii Ginekologicznej w sprawie diagnostyki i leczenia zespołu policystycznych jajników

Milewicz¹,

Kudła²,

Spaczyński³

et al. 2018

Endokrynologia Polska

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“…In the adolescent population, polycystic ovary syndrome (PCOS) typically manifests itself with a combination of menstrual dysfunction and symptoms of hyperandrogenism. So far, a single reason for this syndrome has not been established, but many researchers suggest a complex interplay between genetic and environmental components [7].…”

Section: Polycystic Ovary Syndromementioning

confidence: 99%

Polycystic ovary syndrome (PCOS) and the accompanying disorders of glucose homeostasis among girls at the time of puberty

Otto-Buczkowska

Grzyb

Jainta

2018

Pediatr Endocrino Diabetes Metab

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Polycystic ovary syndrome (PCOS) usually arises during puberty and is marked by insulin resistance, hyperinsulinemia, and hyperandrogenism. The principle is that the diagnosis of PCOS must be based on the presence of at least two of the following three criteria: chronic anovulation, hyperandrogenism (clinical or biological), and polycystic ovaries. The diagnosis of PCOS in adolescents is particularly difficult due to developmental problems in this group. Many symptoms of PCOS, including acne, menstrual irregularities, and hyperinsulinemia, are common in normal puberty. Adolescents with PCOS are at an increased risk of developing health problems later on in life, such as diabetes, cardiovascular disease, and infertility. One should reckon with the frequent occurrence of the PCOS in type 1 diabetes, when the ovaries and the adrenals are exposed to excessive insulin concentrations. Ovarian hyperandrogenism is common in adolescent girls with type 1 diabetes. Methods of treatment for an adolescent with PCOS include diet and exercise. Metformin is commonly used in young girls and adolescents with PCOS as first-line monotherapy or in combination with anti-androgen medications. StreszczenieZespół policystycznych jajników (PCOS) zwykle pojawia się w okresie dojrzewania i charakteryzuje się występowaniem insulinooporności, hiperinsulinemii i hiperandrogenizmu. Przyjęta jest zasada, że diagnoza PCOS musi opierać się na obecności co najmniej dwóch z trzech następujących kryteriów: przewlekłego braku owulacji, hiperandrogenizmu (klinicznego lub biologicznego) i policystycznych jajników. Rozpoznanie PCOS u nastolatek jest szczególnie trudne. Wiele objawów PCOS, w tym trądzik, zaburzenia miesiączkowania i hiperinsulinemia, są częste w okresie dojrzewania. U nastolatek z PCOS istnieje zwiększone ryzyko wystąpienia problemów zdrowotnych w późniejszym życiu, takich jak cukrzyca, choroby sercowo-naczyniowe i niepłodność. Należy liczyć się z częstym występowaniem PCOS w cukrzycy typu 1, gdy jajniki i nadnercza są narażone na nadmierne stężenia insuliny. Hiperandrogenizm pochodzenia jajnikowego występuje często u nastolatek z cukrzycą typu 1. Leczenie młodzieży z PCOS obejmuje dietę i ćwiczenia fizyczne. Metformina jest powszechnie stosowana u młodych dziewcząt z PCOS w monoterapii pierwszego rzutu lub w połączeniu z lekami przeciwandrogenowymi. Słowa kluczowe hiperandrogenizm, zespół policystycznych jajników, insulinooporność, cukrzyca

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