Polycaprolactone/chitosan blend nanofibres electrospun from an acetic acid/formic acid solvent system

Schueren, Lien Van der; Steyaert, Iline; Schoenmaker, Bert De; Clerck, Karen De

doi:10.1016/j.carbpol.2012.01.085

Cited by 126 publications

(79 citation statements)

References 26 publications

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“…The electrospinning solutions were prepared by simultaneously adding certain amounts of PCL and chitosan to a mixed solvent system and stirring for 3 h. The solvent system was composed of formic acid/acetic acid (FA/AA) in a ratio of 70/30 [36,38].…”

Section: Electrospinningmentioning

confidence: 99%

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Effects of Chitosan Concentration on the Protein Release Behaviour of Electrospun Poly(ε‐caprolactone)/Chitosan Nanofibers

Roozbahani

Sultana

Almasi

et al. 2015

Journal of Nanomaterials

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Poly( -caprolactone)/chitosan (PCL/chitosan) blend nanofibers with different ratios of chitosan were electrospun from a formic acid/acetic acid (FA/AA) solvent system. Bovine serum albumin (BSA) was used as a model protein to incorporate biochemical cues into the nanofibrous scaffolds. The morphological characteristics of PCL/chitosan and PCL/chitosan/BSA Nanofibers were investigated by scanning electron microscopy (SEM). Fourier transform infrared spectroscopy (FTIR) was used to detect the presence of polymeric ingredients and BSA in the Nanofibers. The effects of the polymer blend ratio and BSA concentration on the morphological characteristics and consequently on the BSA release pattern were evaluated. The average fiber diameter and pore size were greater in Nanofibers containing BSA. The chitosan ratio played a significant role in the BSA release profile from the PCL/chitosan/BSA blend. Nanofibrous scaffolds with higher chitosan ratios exhibited less intense bursts in the BSA release profile.

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Section: Electrospinningmentioning

confidence: 99%

“…In 2012 [36] introduced a solution system consisting of formic acid/acetic acid (FA/AA) as a substitute for previous expensive and toxic solvents [32,33,37]. This new solvent system opens the door for further feasibility studies for PCL/chitosan scaffolds as means to simulate the basic requirements of ECM.…”

Section: Introductionmentioning

confidence: 99%

Effects of Chitosan Concentration on the Protein Release Behaviour of Electrospun Poly(ε‐caprolactone)/Chitosan Nanofibers

Roozbahani

Sultana

Almasi

et al. 2015

Journal of Nanomaterials

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“…Moreover, it has been stated that PCL shows a good miscibility with various polymers and improves the process ability of some polymers [15]. Hence, blending PCL with chitosan would most likely assist the electrospinning process of chitosan [16].…”

Section: Introductionmentioning

confidence: 99%

Fabrication of Curcumin Loaded Nano Polycaprolactone/Chitosan Nonwoven Fabric via Electrospinning Technique

Hoang¹

2018

JST

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Cucurmin loaded poly ε-caprolactone/chitosan (PCL/CTS) nanoscale nonwoven fabric was successfully fabricated using electrospinning, a facial and efficient method. The surface tensions of PCL/CTS blend solutions in various ratios were measured to evaluate the influence of PCL/CTS ratio on fibers formation. The effects of process parameter such as the applied voltage, tip-collector distance and the solution flow rate on the fiber generation and morphology of final fiber were optimized. Nanofibers morphology and structure were characterized by scanning electron microscopy (SEM) and transmission electron microscopy (TEM), respectively. The prepared fibers had a smooth surface and fine morphology. The diameter of fibers ranges from 200 nm to 400 nm. The release kinetics of curcumin loaded samples were also analyzed via in vitro technique. Results demonstrated that the polycaprolactone/chitosan-based nanofibers encapsulate curcumin is a potential material for wound healing acceleration.

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“…Así mismo, aparecen las vibraciones correspondientes al enlace O-Ti-O en el titanato de sodio, en la zona de longitudes de onda comprendidas entre 1041-1047 cm −1 . La falta de formación de nuevos enlaces sugiere que la interacción entre la policaprolactona y el quitosano en las películas es atribuida a un fenómeno de interacción física entre los biopolímeros por la unión por puentes de hidrógeno entre el grupo carbonilo de la policaprolactona y los grupos amino e hidroxilo del quitosano (Vera et al, 2010;Van der Schueren et al, 2012).…”

Section: Caracterización Por Espectroscopia Infrarroja (Ftir)unclassified

Obtención, caracterización y evaluación in vitro de recubrimientos de policaprolactona-quitosano sobre la aleación Ti6Al4V tratada químicamente

Rodríguez¹,

Quintero-Jaime²,

Ballesteros³

et al. 2014

REVMETAL

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RESUMEN:Se obtuvieron recubrimientos poliméricos de policaprolactona-quitosano, aplicados mediante la técnica Dip-Coating, sobre sustratos de Ti6Al4V tratados químicamente con NaOH. Con base en los análisis SEM y los espectros infrarrojos, se observó que la cantidad de policaprolactona en el recubrimiento presentó un efecto en la retención de quitosano en la superficie, relacionado con la emisión del enlace R-OH y las características morfológicas. Los espectros de impedancia realizados a las películas poliméricas, mostraron procesos relacionados con fenómenos de adsorción de especies iónicas hasta la formación de monocapas en la superficie. Igualmente, estos espectros mostraron fenómenos de transferencia de carga generados por las características morfológicas de los recubrimientos, como sus porosidades, densidad y homogeneidad. La inmersión de los sustratos recubiertos en una solución SBF durante 8 días, permitió observar su capacidad de adsorción de calcio mediante la nucleación y precipitación de fosfatos de calcio, mostrando un carácter bioactivo frente al medio. ABSTRACT: Obtention, characterization and in vitro evaluation of polycaprolactone-chitosan coatings growth on chemically treated Ti6Al4V alloy. Polymeric coatings were obtained polycaprolactone-chitosan. The coatings were applied by dip-coating technique, on Ti6Al4V substrates chemically treated with NaOH solution. Based on SEM morphological analysis and infrared spectra, it was observed that the amount of polycaprolactone in the coating obtained had an effect in retaining the chitosan on the surface, associated with the emission of R-OH bond and the morphological characteristics. Impedance spectra performed on the polymeric films showed phenomena related processes adsorption of ionic species to monolayer formation on the surface. These spectra showed equally charge transfer phenomena generated by the morphological characteristics of the coatings, such as its porosity, density and homogeneity. The coated substrate was immersing in SBF solution for 8 days, allowed to observe its adsorption capacity of calcium through nucleation and precipitation of calcium phosphates, bioactive character displaying a front medium.

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Polycaprolactone/chitosan blend nanofibres electrospun from an acetic acid/formic acid solvent system

Cited by 126 publications

References 26 publications

Effects of Chitosan Concentration on the Protein Release Behaviour of Electrospun Poly(ε‐caprolactone)/Chitosan Nanofibers

Effects of Chitosan Concentration on the Protein Release Behaviour of Electrospun Poly(ε‐caprolactone)/Chitosan Nanofibers

Fabrication of Curcumin Loaded Nano Polycaprolactone/Chitosan Nonwoven Fabric via Electrospinning Technique

Obtención, caracterización y evaluación in vitro de recubrimientos de policaprolactona-quitosano sobre la aleación Ti6Al4V tratada químicamente

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