Poly(glycidyl methacrylate) beads embedded cryogels for pseudo-specific affinity depletion of albumin and immunoglobulin G

Poly(hydroxyethyl methacrylate) based affinity cryogel for plasmid DNA purification

“…This is a significant problem when using conventional chromatographic media, which consists of small pores that are not engineered to handle large molecules [1]. Alternatives to porous particles are the use of membrane and monolith-technology, which overcome the diffusion limitation, as well as to improve the binding capacity of the support for the target molecules, which is also considered to be a limiting factor in pDNA chromatography [5][6][7][8]. Large pores and the absence of transport limitations make adsorptive membranes an attractive option for the purification of pDNA [9].…”

Molecularly imprinted composite cryogels for hemoglobin depletion from human blood

“…However, big pores bring along a disadvantage, which is low surface area to cryogels that results in low binding capacity of cryogel column (Yao et al, 2007;Baydemir et al, 2009;Aslıyüce et al, 2010;Koç et al, 2011;Hajizadeh et al, 2012). Composite cryogels increase the surface area by embedding microspheres because of high surface area of microspheres (Yao et al, 2006;Le Noir et al, 2007;Bereli et al, 2010;Ivanov et al, 2012;Sun et al, 2012a;Sun et al, 2012b).…”

Investigation of Swelling, Adsorption and Mechanical Properties of Sodium Acrylate Based Hydrogel and Cryogels

“…Kriyojeller, yarı-donmuş sulu ortamda sentezlenen, heterojen açık gözenek yapısına sahip yapılar olup, yüksek mekanik dayanım ve elastikiyet özelliği gösterirler. Bununla birlikte, kriyojellerin geniş gözenekli yapıları sebebiyle adsorpsiyon kapasiteleri düşüktür [5]- [7].…”