Poly(3,4-ethylenedioxythiophene)-modified Ni/silicon microchannel plate electrode for the simultaneous determination of ascorbic acid, dopamine and uric acid

Abstract

A Ni/silicon microchannel plate (Ni/Si MCP) electrode modified with poly(3,4-ethylenedioxythiophene) (PEDOT) was successfully fabricated. The analytical performance of prepared electrode for the simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA) was investigated by using cyclic voltammetry and differential pulse voltammetry (DPV). The sensitivities for AA, DA and UA obtained by DPV are 5.39 A m(-2) mM(-1), 0.054 A m(-2) μM(-1) and 0.022 A m(-2) μM(-1), respectively. The calculated detection limits were 10 μM (AA), 1.5 μM (DA) and 2.7 μM (UA). The prepared electrode was successfully applied to the detection of AA, DA and UA in urine samples. The experiments illustrate that Ni/Si MCP is a good electrode material which provides a large surface-to-volume ratio and enhances the selectivity and sensitivity.

A highly sensitive sensor for simultaneous determination of ascorbic acid, dopamine and uric acid based on ultra-small Ni nanoparticles

“…Especially, the proposed sensor significantly improves sensitivity for the determination of AA, DA and UA. As compared with the similar work that Yu et al [34] developed a electrochemical sensor based on Poly(3,4-ethylenedioxythiophene)-modified Ni/silicon microchannel plate electrode for the determination of AA, DA and UA, the much higher sensitivity could be originating from the electrocatalytic activity of Ni NPs with ultra-small size, especially the DA with sensitivity of 45.571 μA cm −2 μM −1 and UA of 11.873 μA cm − 2 μM − 1 respectively with other two exist. It demonstrated that Ni NPs get larger specific surface area for the extraordinary electrocatalytic activities owing to the such small size.…”

A glassy carbon electrode modified with MoS2 nanosheets and poly(3,4-ethylenedioxythiophene) for simultaneous electrochemical detection of ascorbic acid, dopamine and uric acid

“…However, the sensitivity of PEDOT modified GCEs show relative low sensitivity to the simultaneous detection of AA, DA and UA compared with other materials modified GCE. In order to improve its sensitivity, Ni/silicon microchannel plate electrode was used to replace GCE [7]. The disadvantage of this strategy is the complex of fabrication process of Ni/silicon microchannel plate electrode.…”

“…In order to overcome the overlap of their voltammetric responses, various materials have been used for the modification of electrodes to achieve the simultaneous detection of AA, DA and UA. For examples, poly(3,4-ethylenedioxythiophene) (PEDOT) [5][6][7], MWCNT-PEDOT composite [8], poly (sulfonazo III) [9] and iron ion-doped natrolite zeolitemultiwalled carbon nanotube [10] were reported for the detection of AA, DA and UA.…”

Synthesis of NiCo2O4/Nano-ZSM-5 nanocomposite material with enhanced electrochemical properties for the simultaneous determination of ascorbic acid, dopamine, uric acid and tryptophan

“…14 Application of the zeolite in the construction of electrochemical sensor is limited because it does not contain any redox metal. [34][35][36] Though there are numerous reports available in literature for the simultaneous electrochemical determination of two or three such molecules. Our research group has developed a wide range of structure directing agents for the synthesis of ordered and disordred nanocrystlline zeolites of different framework structures.…”