“…15,16) Despite these studies, the application of RVS as a food additive or source of pharmaceutical ingredients has been limited, because urushiol derivatives in RVS are known to cause irritation, inflammation or blistering in sensitive individuals, a reaction known as urushiolinduced contact dermatitis. 17) For this reason, research has been focused on removing urushiol derivatives from RSV by heat treatment, solvent extraction, far-infrared radiation, and enzyme treatment. 18) Nevertheless, little information is available on the health effects of detoxified R. verniciflua Stokes (DRVS) devoid of urushiol.…”