Points to Consider When Choosing A Biopsy Method in Cases of Pleurisy of Unknown Origin

Cantó, A.; Rivas, J.; Saumench, J.; Morera, R.; Moya, Juan

doi:10.1016/s0012-3692(15)33487-5

Cited by 44 publications

(14 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…From clinical observations, it is known that cancers disseminated in the pleural cavity, with the exception of lung cancer progressively involving the ipsilateral pleural cavity, are frequently found in the posterior inferior part of the parietal pleura in early-stage disease. Thus, some authors have speculated that primary pleural cancer develops from the parietal or diaphragmatic pleura and invades the visceral pleura [Canto et al, 1990;Boutin et al, in press]. Such a hypothesis takes into account the difference in prognosis of malignancies localized on the parietal pleura or involving the visceral pleura.…”

Section: Discussionmentioning

confidence: 99%

“Patient‐Like” nude mouse metastatic model of advanced human pleural cancer

Astoul

Colt

Wang

et al. 1994

J of Cellular Biochemistry

View full text Add to dashboard Cite

Pleural cancer in humans is a frequently occurring tumor. Recently, clinical trials have suggested that chemotherapy and immunotherapy administered intrapleurally may elicit responses in early-stage diseases. However, at radiological and pleural endoscopic evaluation, most of the patients are found to have a visceral pleural involvement that is generally refractory to therapy and leads to a poor prognosis. The goal of this study was to construct a nude mouse model of human parietal- and visceral-pleural cancer that could reflect the clinical picture for this disease. The model could then be useful for drug discovery for pleural cancer. A well-differentiated human lung adenocarcinoma was used as intact tissue for implantation. Ten mice underwent parietal-pleural implantation and ten mice visceral-pleural implantation via a novel thoracotomy procedure we have developed. Symptoms of tumor growth were determined from weight loss, respiratory distress, or debilitation. Actual tumor growth and spread were measured at autopsy. The mouse survival curves of each group were estimated by the Kaplan-Meier method and the difference of the median survival times was assessed by the Log-rank test. The slopes of mean-mouse weight curves were compared using a standard two-sample t-test. A 100% take rate was achieved in constructing the pleural cancer models. Tumor growth was initially assessed by symptomatology and survival: the median survival time was, respectively, 27.9 days and 31 days for visceral-pleural and parietal-pleural implanted groups (P < 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

show abstract

Section: Discussionmentioning

confidence: 99%

“Patient‐Like” nude mouse metastatic model of advanced human pleural cancer

Astoul

Colt

Wang

et al. 1994

J of Cellular Biochemistry

View full text Add to dashboard Cite

show abstract

“…Low diagnostic value of pleural biopsy depends on costal pleural involvement of cancer cells in only half of patients with MPE since initial metastatic disease most commonly occurs on the visceral, mediastinal, and diaphragmatic pleurae [54].…”

Section: Pleura and Fluid Characteristicsmentioning

confidence: 99%

“…The specificity of closed needle biopsy for MPE is high, but case series report sensitivities that range from 7% to 72% [53,[55][56][57]. However, closed pleural biopsy adds little to the cytological diagnosis in most cases and this is related to the scarce and irregular distribution of the tumour lesions in the pleural cavity when cytology is negative [54]. The yield of blind needle biopsy is higher when the pleural lesions are diffuse, as in tuberculosis and advanced neoplastic disease.…”

Section: Pleura and Fluid Characteristicsmentioning

confidence: 99%

Management of Malignant Pleural Effusion

Eşme¹,

Çalık²

2013

Principles and Practice of Cardiothoracic Surgery

View full text Add to dashboard Cite

“…However, it has been shown that many of these patients have effusions only when their visceral pleural is involved [1,6]. The visceral involvement represents hematogenous spread of cancer and leads to secondary metastases to the pleural space and parietal side.…”

Section: Pathogenesismentioning

confidence: 99%