“…Senescence has been studied successfully in T lymphocytes, skin, and intramuscular fat, and high-throughput methods will be available soon (Evangelou et al, 2016;Lozano-Torres et al, 2017). In addition, specific patterns of circulating proteins may exist that indirectly estimate the burden of senescence (Angelini et al, 2017;Hoffman, Lyu, Pletcher, & Promislow, 2017;Kadota et al, 2018;Menni et al, 2014;Tanaka et al, 2018;Yousefzadeh et al, 2017). Similarly, measures of autophagy are routinely used in mammalian studies and should be applicable to humans (Klionsky, 2014;Klionsky, Cuervo, & Seglen, 2007;Menzies, Moreau, Puri, Renna, & Rubinsztein, 2012).…”