Plasma ascorbic acid level and erythrocyte fragility in preeclampsia and eclampsia

Plasma vitamin C assay in women of reproductive age in Kampala, Uganda, using a colorimetric method

“…Mean plasma vitamin C concentration was lowest in women with pre-eclampsia, followed by women with normal pregnancy; it was highest in nonpregnant women. These results confirm those of Bowen et al (1998), Kharb (2000) and Zhang et al (2002), but differ from others (Ozan et al 1997;Bowen et al 2001). Bowen et al (1998) found plasma vitamin C concentrations to be higher in non-pregnant than pregnant women; women with pre-eclampsia had the lowest vitamin C concentrations.…”

Serum advanced oxidation protein products, myeloperoxidase and ascorbic acid in pre‐eclampsia and eclampsia

“…It has been suggested that there is a deficiency in the protective antioxidant systems or increased utilisation of antioxidants in pre-eclampsia compared with normal pregnancy. 8 Contrary to many other studies 9,23 suggesting a role of oxidative stress in pre-eclampsia, some reports 8,24,25 documented that there were no significant differences between the oxidant or antioxidant activity or both in pre-eclampsia and in normal pregnancy. We found significant increase in MDA levels, an indicator of lipid peroxidation, in pre-eclampsia and eclampsia as compared to healthy pregnancy.…”

Oxidative stress in infants born to preeclamptic mothers

“…26 Contrary to many other studies suggesting a role of oxidative stress in preeclampsia, some reports documented that oxidant or antioxidant activity or both did not differ in preeclampsia from normal pregnancy. 16,17,27,28 We performed the present study to evaluate oxidative stress in infants born to preeclamptic mothers. Therefore, we analyzed MDA and GSH levels, and SOD and GPx activities in cord plasma and compared the results of preeclamptic group with those of the controls.…”