Plant Essential Oil with Biological Activity

Elshafie, Hazem S.

doi:10.3390/plants11070980

Cited by 7 publications

(3 citation statements)

References 13 publications

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“…Low concentrations of CO (0.125%) signi cantly inhibited bio lm formation of S. mutans compared to the non-treated control. Similar observations in disintegration of bio lm formation were observed in Acinetobacter baumannii, Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa and other important nosocomial pathogens 11,44,45 . This places CO as a potential essential antimicrobial alternative in treating oral pathogens and nosocomial pathogens.…”

Section: Discussionsupporting

confidence: 79%

Anti-microbial activity and biofilm inhibition of Streptococcus mutans by Coriandrum sativum essential oil and isothiocyanates

Ngalah

Hansen

Frank³

et al. 2023

Preprint

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Aims This study evaluated the antimicrobial effect of coriander oil (CO) and isothiocyanates (ITC; Allyl, Benzyl and Phenyl-A-, B-, P-ITC) on clinical oral isolate Streptococcus mutans. We evaluated inhibition of biofilm, metabolic activity and exopolysaccharide formation. Methods The composition of CO was determined by gas chromatography- mass spectrometry (GC-MS). CO and ITC were dissolved in 0.1% Tween 80. Different concentrations (0.0039-1%) of CO, ITC and CO-ITC were made in Tryptic soy broth (TSB) and with sucrose (TSBS). Broth dilution method was used to determine the minimum inhibitory concentration (MIC). Minimum biofilm inhibitory concentrations (MBIC) were established by staining biofilm with crystal violet. Checkerboard assay was used to evaluate combination effects. An XTT assay was used to determine the metabolic activity and a sulphuric acid-phenol assay for inhibition of S. mutans exopolysaccharide production. Results CO was dominated by Linalool (65.5%) followed by 2-bornanone (6.16%) and Gamma-terpinene (4.31%). The least was Terpinen-4-ol (0.13%). The MIC of CO was 0.00195% and < 0.00195% for ITCs. MBIC for B-ITC was at < 0.0039%, while with CO-ITC at 0.00195% (p < 0.05). The MBC of CO was 0.125% and for CO-B-ITC MBIC was < 0.00195%. The B-ITC MBC was > 0.25%. Strong S. mutans exopolysaccharide inhibition was observed with ITC and CO at 0.0039%. CO reduced S. mutans metabolic activity at 0.125% and ITC at 0.0078%. Conclusion and clinical relevance: CO and ITC are promising agents in prevention of both periodontal disease and dental caries. Further data is required to warrant development of products to help mitigate dental caries and periodontal disease.

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Section: Discussionsupporting

confidence: 79%

Anti-microbial activity and biofilm inhibition of Streptococcus mutans by Coriandrum sativum essential oil and isothiocyanates

Ngalah

Hansen

Frank³

et al. 2023

Preprint

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“…The chemical composition of Citrus EO has been extensively studied and several compositional patterns owing to the species/cultivars, origin, climate, season, ripening stage, extraction and analytical methods have been published [8][9][10]. The chemical composition of EO of sour orange (Citrus aurantium) was assessed in different plant parts during different seasons.…”

Section: Introductionmentioning

confidence: 99%

Essential Oil of Citrus aurantium L. Leaves: Composition, Antioxidant Activity, Elastase and Collagenase Inhibition

et al. 2022

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Sour orange (Citrus aurantium L.), which belongs to the Rutaceae family, is used around the Mediterranean Sea for ornamental and agronomic purposes as a rootstock for the Citrus species. Peels and flowers, the most-used parts of Citrus aurantium L., have constituted a largely promising area of research for their many medicinal properties. However, the leaves of sour orange have not yet been studied extensively. The present study aimed at investigating the essential oil composition of sour orange leaves grown in Algeria and determining their antioxidant and anti-inflammatory properties. Essential oil composition of leaves harvested before flowering was determined by GC-MS. Total phenol content, antioxidant activities (DPPH) and elastase and collagenase inhibition were assessed. Forty-three volatile compounds were detected in essential oil from leaves with a yield of 0.57%. The major compounds were linalool, linalyl acetate and α-Terpineol. Results show that the total phenol content and antioxidant activity of essential oil are low, 3.48 ± 0.10 mg/g (Gallic Acid Equivalent/EO) and IC50 > 10,000 mg·L−1, respectively. In contrast, EO present an interesting level of elastase and collagenase inhibition. This result emphasizes the potential interest of the essential oil of sour orange mainly in relation to its anti-aging mechanism.

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“…They are mainly found in leaves but also in fruits and flowers. The extraction of EOs, generally by the traditional technique of steam distillation and now by the modern supercritical carbon dioxide extraction technique, has very low yields (around 1%), generating highly concentrated volatile mixtures of EOs [ 16 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 ].…”

Section: Essential Oilsmentioning

confidence: 99%

Essential Oils and Melatonin as Functional Ingredients in Dogs

Ruiz-Cano¹,

Sánchez-Carrasco²,

Mihyaoui

et al. 2022

Animals

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The use of nutraceuticals or functional ingredients is increasingly widespread in human food; their use is also widespread in animal feed. These natural compounds generally come from plant materials and comprise a wide range of substances of a very diverse chemical nature. In animals, these compounds, so-called phytogenics, are used to obtain improvements in feed production/stability and also as functional components with repercussions on animal health. Along with polyphenols, isoprenoid compounds represent a family of substances with wide applications in therapy and pet nutrition. Essential oils (EOs) are a group of complex substances with fat-soluble nature that are widely used. Melatonin is an indolic amine present in all living with amphiphilic nature. In this work, we present a review of the most relevant phytogenics (polyphenol, isoprenoid, and alkaloid compounds), their characteristics, and possible uses as nutraceuticals in dogs, with special emphasis on EOs and their regulatory aspects, applied in foods and topically. Additionally, a presentation of the importance of the use of melatonin in dogs is developed, giving physiological and practical aspects about its use in dog feeding and also in topical application, with examples and future projections. This review points to the combination of EOs and melatonin in food supplements and in the topical application as an innovative product and shows excellent perspectives aimed at addressing dysfunctions in pets, such as the treatment of stress and anxiety, sleep disorders, alopecia, and hair growth problems, among others.

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Plant Essential Oil with Biological Activity

Cited by 7 publications

References 13 publications

Anti-microbial activity and biofilm inhibition of Streptococcus mutans by Coriandrum sativum essential oil and isothiocyanates

Anti-microbial activity and biofilm inhibition of Streptococcus mutans by Coriandrum sativum essential oil and isothiocyanates

Essential Oil of Citrus aurantium L. Leaves: Composition, Antioxidant Activity, Elastase and Collagenase Inhibition

Essential Oils and Melatonin as Functional Ingredients in Dogs

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