PLA-HA Scaffolds: Preparation and Bioactivity

Tanodekaew, Siriporn; Channasanon, Somruethai; Kaewkong, Pakkanun; Uppanan, Paweena

doi:10.1016/j.proeng.2013.05.104

Cited by 48 publications

(24 citation statements)

References 10 publications

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“…Materials Science and Engineering C xxx (2015) xxx-xxx Presently, new composite systems combining advantages of polymers and ceramics arise as viable options to fulfill several demands needed for their application in bone tissue regeneration [25]. Several studies reported the osteoconductivity induced by HA [4,[26][27][28]. However, it has poor biodegradability, contrarily to β-TCP which presents a 10 times higher degradation rate [4,29].…”

Section: Introductionmentioning

confidence: 99%

Production and characterization of chitosan/gelatin/β-TCP scaffolds for improved bone tissue regeneration

Serra

Fradique

Vallejo

et al. 2015

Materials Science and Engineering: C

135

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Section: Introductionmentioning

confidence: 99%

Production and characterization of chitosan/gelatin/β-TCP scaffolds for improved bone tissue regeneration

Serra

Fradique

Vallejo

et al. 2015

Materials Science and Engineering: C

135

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“…Process and Material PLA is a thermoplastic widely used for 3D additive manufacturing. It is adaptable and has been used together with SLS [34,142], FDM [143][144][145][146][147][148][149], and light-assisted techniques [61,150]. For light-assisted fabrication, photopolymerizable PLA can be synthesized by methacrylation and mixed with a photo-initiator to form light active photoresin.…”

Section: Polylactic Acid (Pla)mentioning

confidence: 99%

Engineered 3D Polymer and Hydrogel Microenvironments for Cell Culture Applications

2019

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The realization of biomimetic microenvironments for cell biology applications such as organ-on-chip, in vitro drug screening, and tissue engineering is one of the most fascinating research areas in the field of bioengineering. The continuous evolution of additive manufacturing techniques provides the tools to engineer these architectures at different scales. Moreover, it is now possible to tailor their biomechanical and topological properties while taking inspiration from the characteristics of the extracellular matrix, the three-dimensional scaffold in which cells proliferate, migrate, and differentiate. In such context, there is therefore a continuous quest for synthetic and nature-derived composite materials that must hold biocompatible, biodegradable, bioactive features and also be compatible with the envisioned fabrication strategy. The structure of the current review is intended to provide to both micro-engineers and cell biologists a comparative overview of the characteristics, advantages, and drawbacks of the major 3D printing techniques, the most promising biomaterials candidates, and the trade-offs that must be considered in order to replicate the properties of natural microenvironments.

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“…Among all available SFF processes, stereolithography is considered to have the highest achievable resolution, particularly with short-pulse multiphoto laser absorptions [14,[36][37][38], thus attracting much attention in precision fabrication of porous structures. With high-precision microstereolithography (/¿-SLA), polymeric scaffolds with submicron resolution have been fabricated [39^14].…”

Section: Porogen Template Fabricationmentioning

confidence: 99%

Porogen Templating Processes: An Overview

Hong

Zhou

Yao

2014

Journal of Manufacturing Science and Engineering

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Porous materials with wett-defined pore shapes, sizes and distributions are highly desired in many emerging applications, particularly for biomédical materiats and devices. However, conventionat methods for processing porous materiats only demonstrated limited capability in morphological control. One promising solution is the porogen templating process, where a structured porogen pattern is created first and subsequently used as a template or mold for generation of the desired porous material. Particularly, with solid freeform fabrication, porogen temptates having complex internal structures can be additivety fabricated, and they can then be used as motdsfor motding of porous materiats and devices. This articte attempts to offer a constructive overview on the state of the art of porogen patterning and inverse motding, with the goat of exptaining the working mechanisms and providing unbiased accounts of the pros and cons of existing techniques and process variants. The article further intends to provide a fundamental understanding of the constituent elements and corresponding building blocks in porogen templating processes. An increased understanding of these elements will facilitate the development of more capable new processes.

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PLA-HA Scaffolds: Preparation and Bioactivity

Cited by 48 publications

References 10 publications

Production and characterization of chitosan/gelatin/β-TCP scaffolds for improved bone tissue regeneration

Production and characterization of chitosan/gelatin/β-TCP scaffolds for improved bone tissue regeneration

Engineered 3D Polymer and Hydrogel Microenvironments for Cell Culture Applications

Porogen Templating Processes: An Overview

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