Pimecrolimus Cream, 1%, vs Hydrocortisone Acetate Cream, 1%, in the Treatment of Facial Seborrheic Dermatitis: A Randomized, Investigator-Blind, Clinical Trial

Randomized trial of pimecrolimus cream versus triamcinolone acetonide paste in the treatment of oral lichen planus

“…It has been proven to be effective in various inflammatory skin diseases, eg, seborrheic dermatitis, 25 cutaneous lupus erythematosus, vitiligo, and psoriasis. 26 In addition, some case reports have shown its safety and successful use in the treatment of children with anogenital lichen sclerosus and children with lichen aureus.…”

Results of a randomized, double-blind, vehicle-controlled efficacy trial of pimecrolimus cream 1% for the treatment of moderate to severe facial seborrheic dermatitis

“…[10][11][12][13][14] The FDA recently recommended black box warnings for topical calcineurin inhibitors based on animal studies using high doses of these drugs, which suggested a possible increased rate of malignancy. 15 To date, use of pimecrolimus twice daily has been shown to be effective for treatment of seborrheic dermatitis in 4 open-label or single-blind trials involving 11 patients, 16 5 patients, 17 19 patients, 18 and 37 patients, 19 respectively. In addition, several single case reports have described complete clearing of severe facial seborrheic dermatitis within 30 days of twice-daily use of pimecrolimus cream 1%.…”

Topical Pimecrolimus 1% Cream for Resistant Seborrheic Dermatitis of the Face

“…[15] Following the reports of case series, studies investigating the efficacy of pimecrolimus 1% cream in seborrheic dermatitis have been performed. [16,17] Recently, Warshaw et al, [13] Rallis et al, [8] and Firooz et al [16] have demonstrated successful results in their studies. Pimecrolimus may offer advantages over topical corticosteroids.…”